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Gene editing with CRISPR-Cas12a guides possessing ribose-modified pseudoknot handles.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26989-z
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Effect of 2′-5′/3′-5′ phosphodiester linkage heterogeneity on RNA interference.
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- Nucleic Acids Research, 2020, v. 48, n. 9, p. 4643, doi. 10.1093/nar/gkaa222
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- Article
Extensive CRISPR RNA modification reveals chemical compatibility and structure-activity relationships for Cas9 biochemical activity.
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- Nucleic Acids Research, 2019, v. 47, n. 2, p. 546, doi. 10.1093/nar/gky1214
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- Article