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Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors.
Published in:
Oncogene, 2008, v. 27, n. 29, p. 4086, doi. 10.1038/onc.2008.49
By:
- Steelman, L. S.;
- Navolanic, P. M.;
- Sokolosky, M. L.;
- Taylor, J. R.;
- Lehmann, B. D.;
- Chappell, W. H.;
- Abrams, S. L.;
- Wong, E. W. T.;
- Stadelman, K. M.;
- Terrian, D. M.;
- Leslie, N. R.;
- Martelli, A. M.;
- Stivala, F.;
- Libra, M.;
- Franklin, R. A.;
- McCubrey, J. A.
Publication type:
Article
A model of its kind. A century of medicine at Johns Hopkins.
Published in:
1989
By:
- Harvey, A M;
- Brieger, G H;
- Abrams, S L;
- McKusick, V A
Publication type:
journal article
THE ROLE OF α-ADRENOCEPTOR BLOCKADE IN THE TREATMENT OF HYPERTENSION.
Published in:
Journal of Clinical Pharmacy & Therapeutics, 1983, v. 8, n. 2, p. 175, doi. 10.1111/j.1365-2710.1983.tb01048.x
By:
- Abrams, S. M. L.;
- Turner, P.
Publication type:
Article
Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention.
Published in:
2014
By:
- McCubrey, J A;
- Steelman, L S;
- Bertrand, F E;
- Davis, N M;
- Abrams, S L;
- Montalto, G;
- D'Assoro, A B;
- Libra, M;
- Nicoletti, F;
- Maestro, R;
- Basecke, J;
- Cocco, L;
- Cervello, M;
- Martelli, A M
Publication type:
journal article
Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention.
Published in:
Leukemia (08876924), 2014, v. 28, n. 1, p. 15, doi. 10.1038/leu.2013.184
By:
- McCubrey, J A;
- Steelman, L S;
- Bertrand, F E;
- Davis, N M;
- Abrams, S L;
- Montalto, G;
- D'Assoro, A B;
- Libra, M;
- Nicoletti, F;
- Maestro, R;
- Basecke, J;
- Cocco, L;
- Cervello, M;
- Martelli, A M
Publication type:
Article
Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy.
Published in:
2011
By:
- Steelman, L. S.;
- Franklin, R. A.;
- Abrams, S. L.;
- Chappell, W.;
- Kempf, C. R.;
- Bäsecke, J.;
- Stivala, F.;
- Donia, M.;
- Fagone, P.;
- Nicoletti, F.;
- Libra, M.;
- Ruvolo, P.;
- Ruvolo, V.;
- Evangelisti, C.;
- Martelli, A. M.;
- McCubrey, J. A.;
- Bäsecke, J
Publication type:
journal article
Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K/PTEN/Akt/mTOR pathway.
Published in:
2011
By:
- Martelli, A. M.;
- Evangelisti, C.;
- Chappell, W.;
- Abrams, S. L.;
- Bäsecke, J.;
- Stivala, F.;
- Donia, M.;
- Fagone, P.;
- Nicoletti, F.;
- Libra, M.;
- Ruvolo, V.;
- Ruvolo, P.;
- Kempf, C. R.;
- Steelman, L. S.;
- McCubrey, J. A.;
- Bäsecke, J
Publication type:
journal article
Involvement of p53 and Raf/MEK/ERK pathways in hematopoietic drug resistance.
Published in:
2008
By:
- McCubrey, J. A.;
- Abrams, S. L.;
- Ligresti, G.;
- Misaghian, N.;
- Wong, E. W. T.;
- Steelman, L. S.;
- Bäsecke, J.;
- Troppmair, J.;
- Libra, M.;
- Nicoletti, F.;
- Molton, S.;
- McMahon, M.;
- Evangelisti, C.;
- Martelli, A. M.;
- Bäsecke, J
Publication type:
journal article
Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia.
Published in:
2008
By:
- Steelman, L. S.;
- Abrams, S. L.;
- Whelan, J.;
- Bertrand, F. E.;
- Ludwig, D. E.;
- Bäsecke, J.;
- Libra, M.;
- Stivala, F.;
- Milella, M.;
- Tafuri, A.;
- Lunghi, P.;
- Bonati, A.;
- Martelli, A. M.;
- McCubrey, J. A.;
- Bäsecke, J
Publication type:
journal article
Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy.
Published in:
Leukemia (08876924), 2008, v. 22, n. 4, p. 708, doi. 10.1038/leu.2008.27
By:
- McCubrey, J. A.;
- Steelman, L. S.;
- Abrams, S. L.;
- Bertrand, F. E.;
- Ludwig, D. E.;
- Bäsecke, J.;
- Libra, M.;
- Stivala, F.;
- Milella, M.;
- Tafuri, A.;
- Lunghi, P.;
- Bonati, A.;
- Martelli, A. M.
Publication type:
Article
Synergy between an IGF-1R antibody and Raf/MEK/ERK and PI3K/Akt/mTOR pathway inhibitors in suppressing IGF-1R-mediated growth in hematopoietic cells.
Published in:
Leukemia (08876924), 2006, v. 20, n. 7, p. 1254, doi. 10.1038/sj.leu.2404217
By:
- Bertrand, F E;
- Steelman, L S;
- Chappell, W H;
- Abrams, S L;
- Shelton, J G;
- White, E R;
- Ludwig, D L;
- McCubrey, J A
Publication type:
Article
Pharmacodynamic and Pharmacokinetic Comparison of Two Formulations of Lorazepam and Placebo.
Published in:
Human Psychopharmacology: Clinical & Experimental, 1988, v. 3, n. 2, p. 133, doi. 10.1002/hup.470030210
By:
- Abrams, S. M. L.;
- Harry, T. V. A.;
- Hedges, A.;
- Murray, G. A.;
- Turner, P.
Publication type:
Article

Found: 12