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The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans.
Published in:
2011
By:
- Menard, Laurence;
- Saadoun, David;
- Isnardi, Isabelle;
- Ng, Yen-Shing;
- Meyers, Greta;
- Massad, Christopher;
- Price, Christina;
- Abraham, Clara;
- Motaghedi, Roja;
- Buckner, Jane H.;
- Gregersen, Peter K.;
- Meffre, Eric
Publication type:
journal article
Corrigendum: Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study.
Published in:
2009
By:
- Silverberg, Mark S;
- Cho, Judy H;
- Rioux, John D;
- McGovern, Dermot P B;
- Wu, Jing;
- Annese, Vito;
- Achkar, Jean-Paul;
- Goyette, Philippe;
- Scott, Regan;
- Xu, Wei;
- Barmada, M Michael;
- Klei, Lambertus;
- Daly, Mark J;
- Abraham, Clara;
- Bayless, Theodore M;
- Bossa, Fabrizio;
- Griffiths, Anne M;
- Ippoliti, Andrew F;
- Lahaie, Raymond G;
- Latiano, Anna
Publication type:
Correction Notice
Ulcerative colitis–risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study.
Published in:
Nature Genetics, 2009, v. 41, n. 2, p. 216, doi. 10.1038/ng.275
By:
- Silverberg, Mark S.;
- Cho, Judy H.;
- Rioux, John D.;
- McGovern, Dermot P. B.;
- Jing Wu;
- Annese, Vito;
- Achkar, Jean-Paul;
- Goyette, Philippe;
- Scott, Regan;
- Wei Xu;
- Barmada, M. Michael;
- Klei, Lambertus;
- Daly, Mark J.;
- Abraham, Clara;
- Bayless, Theodore M.;
- Bossa, Fabrizio;
- Griffiths, Anne M.;
- Ippoliti, Andrew F.;
- Lahaie, Raymond G.;
- Latiano, Anna
Publication type:
Article
Age and CD161 Expression Contribute to Inter-Individual Variation in Interleukin-23 Response in CD8+ Memory Human T Cells.
Published in:
PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0057746
By:
- Shen, Hui;
- Zhang, Wei;
- Abraham, Clara;
- Cho, Judy H.
Publication type:
Article
Effector CD4+ T Cell Expression Signatures and Immune-Mediated Disease Associated Genes.
Published in:
PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0038510
By:
- Wei Zhang;
- Ferguson, John;
- Sok Meng Ng;
- Ken Hui;
- Gerald Goh;
- Aiping Lin;
- Esplugues, Enric;
- Flavell, Richard A.;
- Abraham, Clara;
- Hongyu Zhao;
- Judy H. Cho
Publication type:
Article
Pathway analysis comparison using Crohn's disease genome wide association studies.
Published in:
BMC Medical Genomics, 2010, v. 3, p. 25, doi. 10.1186/1755-8794-3-25
By:
- Ballard, David;
- Abraham, Clara;
- Judy Cho;
- Hongyu Zhao
Publication type:
Article
An inflammatory bowel disease-risk variant in INAVA decreases pattern recognition receptor-induced outcomes.
Published in:
2017
By:
- Jie Yan;
- Hedl, Matija;
- Abraham, Clara;
- Yan, Jie
Publication type:
journal article
ABC transporters and NR4A1 identify a quiescent subset of tissue-resident memory T cells.
Published in:
2016
By:
- Boddupalli, Chandra Sekhar;
- Nair, Shiny;
- Gray, Simon M.;
- Nowyhed, Heba N.;
- Verma, Rakesh;
- Gibson, Joanna A.;
- Abraham, Clara;
- Narayan, Deepak;
- Vasquez, Juan;
- Hedrick, Catherine C.;
- Flavell, Richard A.;
- Dhodapkar, Kavita M.;
- Kaech, Susan M.;
- Dhodapkar, Madhav V.
Publication type:
journal article
Erratum: E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP.
Published in:
Nature Communications, 2017, v. 8, n. 8, p. 16141, doi. 10.1038/ncomms16141
By:
- Bist, Pradeep;
- Cheong, Wan Shoo;
- Ng, Aylwin;
- Dikshit, Neha;
- Kim, Bae Hoon;
- Pulloor, Niyas Kudukkil;
- Khameneh, Hanif Javanmard;
- Hedl, Matija;
- Shenoy, Avinash R.;
- Balamuralidhar, Vanniarajan;
- Malik, Najib Bin Abdul;
- Hong, Michelle;
- Neutzner, Albert;
- Chin, Keh-Chuang;
- Kobayashi, Koichi S.;
- Bertoletti, Antonio;
- Mortellaro, Alessandra;
- Abraham, Clara;
- MacMicking, John D.;
- Xavier, Ramnik J.
Publication type:
Article
Human LACC1 increases innate receptor-induced responses and a LACC1 disease-risk variant modulates these outcomes.
Published in:
Nature Communications, 2017, v. 8, n. 6, p. 15614, doi. 10.1038/ncomms15614
By:
- Lahiri, Amit;
- Hedl, Matija;
- Yan, Jie;
- Abraham, Clara
Publication type:
Article
E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP.
Published in:
Nature Communications, 2017, v. 8, n. 6, p. 15865, doi. 10.1038/ncomms15865
By:
- Bist, Pradeep;
- Cheong, Wan Shoo;
- Ng, Aylwin;
- Dikshit, Neha;
- Kim, Bae-Hoon;
- Pulloor, Niyas Kudukkil;
- Khameneh, Hanif Javanmard;
- Hedl, Matija;
- Shenoy, Avinash R.;
- Balamuralidhar, Vanniarajan;
- Malik, Najib Bin Abdul;
- Hong, Michelle;
- Neutzner, Albert;
- Chin, Keh-Chuang;
- Kobayashi, Koichi S.;
- Bertoletti, Antonio;
- Mortellaro, Alessandra;
- Abraham, Clara;
- MacMicking, John D.;
- Xavier, Ramnik J.
Publication type:
Article
IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine.
Published in:
Nature, 2012, v. 491, n. 7423, p. 259, doi. 10.1038/nature11535
By:
- Huber, Samuel;
- Gagliani, Nicola;
- Zenewicz, Lauren A.;
- Huber, Francis J.;
- Bosurgi, Lidia;
- Hu, Bo;
- Hedl, Matija;
- Zhang, Wei;
- O'Connor, William;
- Murphy, Andrew J.;
- Valenzuela, David M.;
- Yancopoulos, George D.;
- Booth, Carmen J.;
- Cho, Judy H.;
- Ouyang, Wenjun;
- Abraham, Clara;
- Flavell, Richard A.
Publication type:
Article
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
Published in:
Nature, 2012, v. 491, n. 7422, p. 119, doi. 10.1038/nature11582
By:
- Jostins, Luke;
- Ripke, Stephan;
- Weersma, Rinse K.;
- Duerr, Richard H.;
- McGovern, Dermot P.;
- Hui, Ken Y.;
- Lee, James C.;
- Philip Schumm, L.;
- Sharma, Yashoda;
- Anderson, Carl A.;
- Essers, Jonah;
- Mitrovic, Mitja;
- Ning, Kaida;
- Cleynen, Isabelle;
- Theatre, Emilie;
- Spain, Sarah L.;
- Raychaudhuri, Soumya;
- Goyette, Philippe;
- Wei, Zhi;
- Abraham, Clara
Publication type:
Article
A Genome-Wide Scan of Ashkenazi Jewish Crohn's Disease Suggests Novel Susceptibility Loci.
Published in:
PLoS Genetics, 2012, v. 8, n. 3, p. 1, doi. 10.1371/journal.pgen.1002559
By:
- Kenny, Eimear E.;
- Pe'er, Itsik;
- Karban, Amir;
- Ozelius, Laurie;
- Mitchell, Adele A.;
- Sok Meng Ng;
- Erazo, Monica;
- Ostrer, Harry;
- Abraham, Clara;
- Abreu, Maria T.;
- Atzmon, Gil;
- Barzilai, Nir;
- Brant, Steven R.;
- Bressman, Susan;
- Burns, Edward R.;
- Chowers, Yehuda;
- Clark, Lorraine N.;
- Darvasi, Ariel;
- Doheny, Dana;
- Duerr, Richard H.
Publication type:
Article
Regulation of IL-8 and IL-1β expression in Crohn's disease associated NOD2/CARD15 mutations.
Published in:
Human Molecular Genetics, 2004, v. 13, n. 16, p. 1715
By:
- Li, Jing;
- Moran, Thomas;
- Swanson, Eric;
- Julian, Christina;
- Harris, Jeremy;
- Bonen, Denise K.;
- Hedl, Matija;
- Nicolae, Dan L.;
- Abraham, Clara;
- Cho, Judy H.
Publication type:
Article

Found: 15