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Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29688-5
By:
- de Vries, Laura E.;
- Jansen, Patrick A. M.;
- Barcelo, Catalina;
- Munro, Justin;
- Verhoef, Julie M. J.;
- Pasaje, Charisse Flerida A.;
- Rubiano, Kelly;
- Striepen, Josefine;
- Abla, Nada;
- Berning, Luuk;
- Bolscher, Judith M.;
- Demarta-Gatsi, Claudia;
- Henderson, Rob W. M.;
- Huijs, Tonnie;
- Koolen, Karin M. J.;
- Tumwebaze, Patrick K.;
- Yeo, Tomas;
- Aguiar, Anna C. C.;
- Angulo-Barturen, Iñigo;
- Churchyard, Alisje
Publication type:
Article
Using Human Plasma as an Assay Medium in Caco-2 Studies Improves Mass Balance for Lipophilic Compounds.
Published in:
Pharmaceutical Research, 2018, v. 35, n. 11, p. 1, doi. 10.1007/s11095-018-2493-3
By:
- Katneni, Kasiram;
- Pham, Thao;
- Saunders, Jessica;
- Chen, Gong;
- Patil, Rahul;
- White, Karen L.;
- Abla, Nada;
- Chiu, Francis C. K.;
- Shackleford, David M.;
- Charman, Susan A.
Publication type:
Article
Evaluation of the pharmacokinetic-pharmacodynamic relationship of praziquantel in the Schistosoma mansoni mouse model.
Published in:
PLoS Neglected Tropical Diseases, 2017, v. 11, n. 9, p. 1, doi. 10.1371/journal.pntd.0005942
By:
- Abla, Nada;
- Keiser, Jennifer;
- Vargas, Mireille;
- Reimers, Natalie;
- Haas, Helmut;
- Spangenberg, Thomas
Publication type:
Article
Addressing health equity for breastfeeding women: primaquine for Plasmodium vivax radical cure.
Published in:
Malaria Journal, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12936-024-05112-9
By:
- Abla, Nada;
- Marrast, Anne Claire;
- Jambert, Elodie;
- Richardson, Naomi;
- Duparc, Stephan;
- Almond, Lisa;
- Rowland Yeo, Karen;
- Pan, Xian;
- Tarning, Joel;
- Zhao, Ping;
- Culpepper, Janice;
- Waitt, Catriona;
- Koldeweij, Charlotte;
- Cole, Susan;
- Butler, Andrew S.;
- Khier, Sonia;
- Möhrle, Jörg J.;
- El Gaaloul, Myriam
Publication type:
Article
Unanticipated CNS Safety Signal in a Placebo‐Controlled, Randomized Trial of Co‐Administered Atovaquone‐Proguanil and Amodiaquine.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 4, p. 867, doi. 10.1002/cpt.2404
By:
- Chalon, Stephan;
- Chughlay, M. Farouk;
- Abla, Nada;
- Marie Tchouatieu, Andre;
- Haouala, Amina;
- Hutter, Ben;
- Lorch, Ulrike;
- Macintyre, Fiona
Publication type:
Article
Development and application of a PBPK modeling strategy to support antimalarial drug development.
Published in:
CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 9, p. 1335, doi. 10.1002/psp4.13013
By:
- Abla, Nada;
- Howgate, Eleanor;
- Rowland‐Yeo, Karen;
- Dickins, Maurice;
- Bergagnini‐Kolev, Mackenzie C.;
- Chen, Kuan‐Fu;
- McFeely, Savannah;
- Bonner, Jennifer J.;
- Santos, Laura G. A.;
- Gobeau, Nathalie;
- Burt, Howard;
- Barter, Zoe;
- Jones, Hannah M.;
- Wesche, David;
- Charman, Susan A.;
- Möhrle, Jörg J.;
- Burrows, Jeremy N.;
- Almond, Lisa M.
Publication type:
Article
Extrapolation of praziquantel pharmacokinetics to a pediatric population: a cautionary tale.
Published in:
Journal of Pharmacokinetics & Pharmacodynamics, 2018, v. 45, n. 5, p. 747, doi. 10.1007/s10928-018-9601-1
By:
- Bonate, Peter L.;
- Wang, Tianli;
- Passier, Paul;
- Bagchus, Wilhelmina;
- Burt, Howard;
- Lüpfert, Christian;
- Abla, Nada;
- Kovac, Jana;
- Keiser, Jennifer
Publication type:
Article
PBPK‐led assessment of antimalarial drugs as candidates for Covid‐19: Simulating concentrations at the site of action to inform repurposing strategies.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 7, p. 1, doi. 10.1111/cts.13865
By:
- Abla, Nada;
- Almond, Lisa M.;
- Bonner, Jennifer J.;
- Richardson, Naomi;
- Wells, Timothy N. C.;
- Möhrle, Jörg J.
Publication type:
Article
Randomized, placebo‐controlled, double‐blind phase I trial of co‐administered pyronaridine and piperaquine in healthy adults of sub‐Saharan origin.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 4, p. 1, doi. 10.1111/cts.13738
By:
- Kuemmerle, Andrea;
- Gossen, Denis;
- Janin, Annick;
- Stokes, Andrew;
- Abla, Nada;
- Szramowska, Maja;
- Lorch, Ulrike;
- El Gaaloul, Myriam;
- Borghini‐Fuhrer, Isabelle;
- Chalon, Stephan
Publication type:
Article
Characterization of novel PI3Kδ inhibitors as potential therapeutics for SLE and lupus nephritis in pre-clinical studies.
Published in:
Frontiers in Immunology, 2014, v. 5, p. 1, doi. 10.3389/fimmu.2014.00233
By:
- Haselmayer, Philipp;
- Camps, Montserrat;
- Muzerelle, Mathilde;
- El Bawab, Samer;
- Waltzinger, Caroline;
- Bruns, Lisa;
- Abla, Nada;
- Polokoff, Mark A.;
- Jond-Necand, Carole;
- Gaudet, Marilène;
- Benoit, Audrey;
- Meier, Dominique Bertschy;
- Martin, Catherine;
- Gretener, Denise;
- Lombardi, Maria Stella;
- Grenningloh, Roland;
- Ladel, Christoph;
- Petersen, Jørgen Søberg;
- Gaillard, Pascale;
- Hong Ji
Publication type:
Article

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