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SERCA2 regulates proinsulin processing and processing enzyme maturation in pancreatic beta cells.
- Published in:
- Diabetologia, 2023, v. 66, n. 11, p. 2042, doi. 10.1007/s00125-023-05979-4
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- Publication type:
- Article
Erratum to: Autophagy is a major regulator of beta cell insulin homeostasis.
- Published in:
- 2016
- By:
- Publication type:
- Erratum
Autophagy is a major regulator of beta cell insulin homeostasis.
- Published in:
- Diabetologia, 2016, v. 59, n. 7, p. 1480, doi. 10.1007/s00125-016-3868-9
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- Publication type:
- Article
Thyroidal Transcriptomic Profiles of Pathoadaptive Responses to Congenital Hypothyroidism in XB130 Knockout Mice.
- Published in:
- Cells (2073-4409), 2022, v. 11, n. 6, p. 975, doi. 10.3390/cells11060975
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- Publication type:
- Article
Biosynthesis, structure, and folding of the insulin precursor protein.
- Published in:
- Diabetes, Obesity & Metabolism, 2018, v. 20, p. 28, doi. 10.1111/dom.13378
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- Publication type:
- Article
Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39978-1
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- Publication type:
- Article
Structural features of thyroglobulin linked to protein trafficking.
- Published in:
- Protein Science: A Publication of the Protein Society, 2023, v. 32, n. 11, p. 1, doi. 10.1002/pro.4784
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- Publication type:
- Article
Deficient endoplasmic reticulum translocon-associated protein complex limits the biosynthesis of proinsulin and insulin.
- Published in:
- FASEB Journal, 2021, v. 35, n. 5, p. 1, doi. 10.1096/fj.202002774R
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- Publication type:
- Article
Preservation of circadian rhythms by the protein folding chaperone, BiP.
- Published in:
- FASEB Journal, 2019, v. 33, n. 6, p. 7479, doi. 10.1096/fj.201802366RR
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- Publication type:
- Article
G209R Mutant Mouse as a Model for Human PCSK1 Polyendocrinopathy.
- Published in:
- Endocrinology, 2022, v. 163, n. 5, p. 1, doi. 10.1210/endocr/bqac024
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- Publication type:
- Article
Autophagy of the ER: the secretome finds the lysosome.
- Published in:
- FEBS Journal, 2023, v. 290, n. 24, p. 5656, doi. 10.1111/febs.16986
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- Publication type:
- Article
Protein disulfide isomerase-like proteins play opposing roles during retrotranslocation.
- Published in:
- Journal of Cell Biology, 2006, v. 173, n. 6, p. 853, doi. 10.1083/jcb.200602046
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- Publication type:
- Article
Carbonyl Posttranslational Modification Associated With Early-Onset Type 1 Diabetes Autoimmunity.
- Published in:
- 2022
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- Publication type:
- journal article
Erratum. Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes. Diabetes 2021;70:2580-2594.
- Published in:
- 2022
- By:
- Publication type:
- corrected article
The Role of TRAPγ/SSR3 in Preproinsulin Translocation Into the Endoplasmic Reticulum.
- Published in:
- 2022
- By:
- Publication type:
- journal article
Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes.
- Published in:
- 2021
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- Publication type:
- journal article
39-OR: Pancreatic Beta Cell SERCA2 Deficiency Impacts ER-Golgi Vesicle Trafficking and Ceramide Metabolism.
- Published in:
- Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-39-OR
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- Publication type:
- Article
292-OR: Inflammatory Cytokines Rewire the Proinsulin Interaction Network in Human Islets.
- Published in:
- Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-292-OR
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- Publication type:
- Article
Altered β-Cell Prohormone Processing and Secretion in Type 1 Diabetes.
- Published in:
- Diabetes, 2021, v. 70, n. 5, p. 1038, doi. 10.2337/dbi20-0034
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- Publication type:
- Article
Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding.
- Published in:
- 2020
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- Publication type:
- journal article
49-OR: Synergistic Effect of ERAD and Autophagy in Preventing Proinsulin Aggregation and Promoting Beta-Cell Survival.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-49-OR
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- Publication type:
- Article
48-OR: Pancreatic ß Cell SERCA2 Deficiency Leads to Impaired Proinsulin Processing and Reduced ER to Golgi Protein Trafficking.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-48-OR
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- Publication type:
- Article
47-OR: A Reference Map of the Human Proinsulin Biosynthetic Interaction Network.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-47-OR
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- Publication type:
- Article
1893-P: The Integrative Role of ER Protein Quality Control Pathways (ERQC) in Prohormone Maturation.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1893-P
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- Publication type:
- Article
Role of Proinsulin Self-Association in Mutant INS Gene–Induced Diabetes of Youth.
- Published in:
- Diabetes, 2020, v. 69, n. 5, p. 954, doi. 10.2337/db19-1106
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- Publication type:
- Article
343-LB: The Type 2 Diabetes-Associated Lipid Binding Protein STARD10 Controls Insulin Secretory Granule Biogenesis.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-343-LB
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- Publication type:
- Article
2166-P: Sel1L-Hrd1 ERAD Is a Key Regulator of Beta-Cell Function and Identity.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-2166-P
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- Publication type:
- Article
2165-P: In Vivo Islet Imaging Reveals that GLP-1 Paradoxically Increases Insulin Content.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-2165-P
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- Publication type:
- Article
Endoplasmic Reticulum Chaperone Glucose-Regulated Protein 94 Is Essential for Proinsulin Handling.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Chaperone-Driven Degradation of a Misfolded Proinsulin Mutant in Parallel With Restoration of Wild-Type Insulin Secretion.
- Published in:
- 2017
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- Publication type:
- journal article
Disulfide Mispairing During Proinsulin Folding in the Endoplasmic Reticulum.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Monitoring C-Peptide Storage and Secretion in Islet β-Cells In Vitro and In Vivo.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Pancreatic β-Cell Adaptive Plasticity in Obesity Increases Insulin Production but Adversely Affects Secretory Function.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Impaired Cleavage of Preproinsulin Signal Peptide Linked to Autosomal-Dominant Diabetes.
- Published in:
- Diabetes, 2012, v. 61, n. 4, p. 828, doi. 10.2337/db11-0878
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- Publication type:
- Article
In Vivo Misfolding of Proinsulin Below the Threshold of Frank Diabetes.
- Published in:
- Diabetes, 2011, v. 60, n. 8, p. 2092, doi. 10.2337/db10-1671
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- Publication type:
- Article
How Does Type 1 Diabetes Develop? The Notion of Homicide or &beta-Cell Suicide Revisited.
- Published in:
- 2011
- By:
- Publication type:
- Opinion
Defective Thyroglobulin: Cell Biology of Disease.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 13605, doi. 10.3390/ijms232113605
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- Publication type:
- Article
Targeted Induction of Endoplasmic Reticulum Stress Induces Cartilage Pathology.
- Published in:
- PLoS Genetics, 2009, v. 5, n. 10, p. 1, doi. 10.1371/journal.pgen.1000691
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- Publication type:
- Article
Quantitative H<sub>2</sub>S-mediated protein sulfhydration reveals metabolic reprogramming during the Integrated Stress Response.
- Published in:
- eLife, 2015, p. 1, doi. 10.7554/eLife.10067
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- Publication type:
- Article
Inflammatory Cytokines Rewire the Proinsulin Interaction Network in Human Islets.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2022, v. 107, n. 11, p. 3100, doi. 10.1210/clinem/dgac493
- By:
- Publication type:
- Article
Misfolded proinsulin in the endoplasmic reticulum during development of beta cell failure in diabetes.
- Published in:
- Annals of the New York Academy of Sciences, 2018, v. 1418, n. 1, p. 5, doi. 10.1111/nyas.13531
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- Publication type:
- Article
PGRMC1 acts as a size-selective cargo receptor to drive ER-phagic clearance of mutant prohormones.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26225-8
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- Publication type:
- Article
Sox17 Regulates Insulin Secretion in the Normal and Pathologic Mouse β Cell.
- Published in:
- PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0104675
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- Publication type:
- Article
Mutant INS-Gene Induced Diabetes of Youth: Proinsulin Cysteine Residues Impose Dominant-Negative Inhibition on Wild-Type Proinsulin Transport.
- Published in:
- PLoS ONE, 2010, v. 5, n. 10, p. 1, doi. 10.1371/journal.pone.0013333
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- Publication type:
- Article
Dominant-Negative Behavior of Mammalian Vps35 in Yeast Requires a Conserved PRLYL Motif Involved in Retromer Assembly.
- Published in:
- Traffic, 2007, v. 8, n. 12, p. 1829, doi. 10.1111/j.1600-0854.2007.00658.x
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- Publication type:
- Article
Structural Features of Vps35p Involved in Interaction with Other Subunits of the Retromer Complex.
- Published in:
- Traffic, 2007, v. 8, n. 12, p. 1841, doi. 10.1111/j.1600-0854.2007.00659.x
- By:
- Publication type:
- Article
Traffic Interchange Sorting Ourselves Out: Seeking Consensus on Trafficking in the Beta-Cell.
- Published in:
- 2004
- By:
- Publication type:
- Other
Secretory Pathway Quality Control Operating in Golgi, Plasmalemmal, and Endosomal Systems.
- Published in:
- Traffic, 2002, v. 3, n. 11, p. 771, doi. 10.1034/j.1600-0854.2002.31102.x
- By:
- Publication type:
- Article
Adaptation to chronic ER stress enforces pancreatic β-cell plasticity.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32425-7
- By:
- Publication type:
- Article
Distinct states of proinsulin misfolding in MIDY.
- Published in:
- Cellular & Molecular Life Sciences, 2021, v. 78, n. 16, p. 6017, doi. 10.1007/s00018-021-03871-1
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- Publication type:
- Article