Works matching AU Werner, Hauke B.

Results: 43

Curcumin therapy in a Plp1 transgenic mouse model of Pelizaeus-Merzbacher disease.

Published in:

Annals of Clinical & Translational Neurology, 2015, v. 2, n. 8, p. 787, doi. 10.1002/acn3.219

By:

Epplen, Dirk B.;
Prukop, Thomas;
Nientiedt, Tobias;
Albrecht, Philipp;
Arlt, Friederike A.;
Stassart, Ruth M.;
Kassmann, Celia M.;
Methner, Axel;
Nave, Klaus‐Armin;
Werner, Hauke B.;
Sereda, Michael W.

Publication type:

Article

Axonal loss and neuroinflammation caused by peroxisome-deficient oligodendrocytes.

Published in:

Nature Genetics, 2007, v. 39, n. 8, p. 969, doi. 10.1038/ng2070

By:

Kassmann, Celia M.;
Lappe-Siefke, Corinna;
Baes, Myriam;
Brügger, Britta;
Mildner, Alexander;
Werner, Hauke B.;
Natt, Oliver;
Michaelis, Thomas;
Prinz, Marco;
Frahm, Jens;
Nave, Klaus-Armin

Publication type:

Article

Structural myelin defects are associated with low axonal ATP levels but rapid recovery from energy deprivation in a mouse model of spastic paraplegia.

Published in:

PLoS Biology, 2020, v. 18, n. 11, p. 1, doi. 10.1371/journal.pbio.3000943

By:

Trevisiol, Andrea;
Kusch, Kathrin;
Steyer, Anna M.;
Gregor, Ingo;
Nardis, Christos;
Winkler, Ulrike;
Köhler, Susanne;
Restrepo, Alejandro;
Möbius, Wiebke;
Werner, Hauke B.;
Nave, Klaus-Armin;
Hirrlinger, Johannes

Publication type:

Article

Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.77019

By:

Gargareta, Vasiliki-Ilya;
Reuschenbach, Josefine;
Siems, Sophie B.;
Ting Sun;
Piepkorn, Lars;
Mangana, Carolina;
Späte, Erik;
Goebbels, Sandra;
Huitinga, Inge;
Möbius, Wiebke;
Nave, Klaus-Armin;
Jahn, Olaf;
Werner, Hauke B.

Publication type:

Article

Progressive axonopathy when oligodendrocytes lack the myelin protein CMTM5.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.75523

By:

Buscham, Tobias J.;
Eichel-Vogel, Maria A.;
Steyer, Anna M.;
Jahn, Olaf;
Strenzke, Nicola;
Dardawal, Rakshit;
Memhave, Tor R.;
Siems, Sophie B.;
Müller, Christina;
Meschkat, Martin;
Ting Sun;
Ruhwedel, Torben;
Möbius, Wiebke;
Krämer-Albers, Eva-Maria;
Boretius, Susann;
Nave, Klaus-Armin;
Werner, Hauke B.

Publication type:

Article

White matter integrity in mice requires continuous myelin synthesis at the inner tongue.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28720-y

By:

Meschkat, Martin;
Steyer, Anna M.;
Weil, Marie-Theres;
Kusch, Kathrin;
Jahn, Olaf;
Piepkorn, Lars;
Agüi-Gonzalez, Paola;
Phan, Nhu Thi Ngoc;
Ruhwedel, Torben;
Sadowski, Boguslawa;
Rizzoli, Silvio O.;
Werner, Hauke B.;
Ehrenreich, Hannelore;
Nave, Klaus-Armin;
Möbius, Wiebke

Publication type:

Article

Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26880-x

By:

Kettwig, Matthias;
Ternka, Katharina;
Wendland, Kristin;
Krüger, Dennis Manfred;
Zampar, Silvia;
Schob, Charlotte;
Franz, Jonas;
Aich, Abhishek;
Winkler, Anne;
Sakib, M. Sadman;
Kaurani, Lalit;
Epple, Robert;
Werner, Hauke B.;
Hakroush, Samy;
Kitz, Julia;
Prinz, Marco;
Bartok, Eva;
Hartmann, Gunther;
Schröder, Simone;
Rehling, Peter

Publication type:

Article

Abcd2 Is a Strong Modifier of the Metabolic Impairments in Peritoneal Macrophages of Abcd1-Deficient Mice.

Published in:

PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0108655

By:

Muneer, Zahid;
Wiesinger, Christoph;
Voigtländer, Till;
Werner, Hauke B.;
Berger, Johannes;
Forss-Petter, Sonja

Publication type:

Article

Hyccin, the Molecule Mutated in the Leukodystrophy Hypomyelination and Congenital Cataract (HCC), Is a Neuronal Protein.

Published in:

PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0032180

By:

Gazzerro, Elisabetta;
Baldassari, Simona;
Giacomini, Caterina;
Musante, Veronica;
Fruscione, Floriana;
Padula, Veronica La;
Biancheri, Roberta;
Scarfì, Sonia;
Prada, Valeria;
Sotgia, Federica;
Duncan, Ian D.;
Zara, Federico;
Werner, Hauke B.;
Lisanti, Michael P.;
Nobbio, Lucilla;
Corradi, Anna;
Minetti, Carlo

Publication type:

Article

Epitope-Specific Tolerance Modes Differentially Specify Susceptibility to Proteolipid Protein-Induced Experimental Autoimmune Encephalomyelitis.

Published in:

Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01511

By:

Lei Wang;
Winnewisser, Julia;
Federle, Christine;
Jessberger, Gregor;
Nave, Klaus-Armin;
Werner, Hauke B.;
Kyewski, Bruno;
Klein, Ludger;
Hinterberger, Maria

Publication type:

Article

The CNS Myelin Proteome: Deep Profile and Persistence After Post-mortem Delay.

Published in:

Frontiers in Cellular Neuroscience, 2020, v. 14, p. N.PAG, doi. 10.3389/fncel.2020.00239

By:

Jahn, Olaf;
Siems, Sophie B.;
Kusch, Kathrin;
Hesse, Dörte;
Jung, Ramona B.;
Liepold, Thomas;
Uecker, Marina;
Sun, Ting;
Werner, Hauke B.

Publication type:

Article

The transcriptome of mouse central nervous system myelin.

Published in:

Scientific Reports, 2016, p. 25828, doi. 10.1038/srep25828

By:

Thakurela, Sudhir;
Garding, Angela;
Jung, Ramona B.;
Müller, Christina;
Goebbels, Sandra;
White, Robin;
Werner, Hauke B.;
Tiwari, Vijay K.

Publication type:

Article

Transcallosal Projections Require Glycoprotein M6-Dependent Neurite Growth and Guidance.

Published in:

Cerebral Cortex, 2015, v. 25, n. 11, p. 4111, doi. 10.1093/cercor/bhu129

By:

Sakura Mita;
de Monasterio-Schrader, Patricia;
Fünfschilling, Ursula;
Takahiko Kawasaki;
Hidenobu Mizuno;
Takuji Iwasato;
Nave, Klaus-Armin;
Werner, Hauke B.;
Tatsumi Hirata

Publication type:

Article

CMTM6 expressed on the adaxonal Schwann cell surface restricts axonal diameters in peripheral nerves.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-18172-7

By:

Eichel, Maria A.;
Gargareta, Vasiliki-Ilya;
D'Este, Elisa;
Fledrich, Robert;
Kungl, Theresa;
Buscham, Tobias J.;
Lüders, Katja A.;
Miracle, Cristina;
Jung, Ramona B.;
Distler, Ute;
Kusch, Kathrin;
Möbius, Wiebke;
Hülsmann, Swen;
Tenzer, Stefan;
Nave, Klaus-Armin;
Werner, Hauke B.

Publication type:

Article

Microglia ablation alleviates myelin-associated catatonic signs in mice.

Published in:

2018

By:

Janova, Hana;
Arinrad, Sahab;
Balmuth, Evan;
Mitjans, Marina;
Hertel, Johannes;
Habes, Mohamad;
Bittner, Robert A;
Pan, Hong;
Goebbels, Sandra;
Begemann, Martin;
Gerwig, Ulrike C;
Langner, Sönke;
Werner, Hauke B;
Kittel-Schneider, Sarah;
Homuth, Georg;
Davatzikos, Christos;
Völzke, Henry;
West, Brian L;
Reif, Andreas;
Grabe, Hans Jörgen

Publication type:

journal article

Partial Immunoblotting of 2D-Gels: A Novel Method to Identify Post-Translationally Modified Proteins Exemplified for the Myelin Acetylome.

Published in:

Proteomes, 2017, v. 5, n. 1, p. 3, doi. 10.3390/proteomes5010003

By:

Kusch, Kathrin;
Uecker, Marina;
Liepold, Thomas;
Möbius, Wiebke;
Hoffmann, Christian;
Neumann, Heinz;
Werner, Hauke B.;
Jahn, Olaf

Publication type:

Article

Oligodendrocytes support axonal transport and maintenance via exosome secretion.

Published in:

PLoS Biology, 2020, v. 18, n. 12, p. 1, doi. 10.1371/journal.pbio.3000621

By:

Frühbeis, Carsten;
Kuo-Elsner, Wen Ping;
Müller, Christina;
Barth, Kerstin;
Peris, Leticia;
Tenzer, Stefan;
Möbius, Wiebke;
Werner, Hauke B.;
Nave, Klaus-Armin;
Fröhlich, Dominik;
Krämer-Albers, Eva-Maria

Publication type:

Article

Isolated catatonia-like executive dysfunction in mice with forebrain-specific loss of myelin integrity.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.70792

By:

Arinrad, Sahab;
Depp, Constanze;
Siems, Sophie B.;
Sasmita, Andrew Octavian;
Eichel, Maria A.;
Ronnenberg, Anja;
Hammerschmidt, Kurt;
Lüders, Katja A.;
Werner, Hauke B.;
Ehrenreich, Hannelore;
Nave, Klaus-Armin

Publication type:

Article

The NG2 Proteoglycan Protects Oligodendrocyte Precursor Cells against Oxidative Stress via Interaction with OMI/HtrA2.

Published in:

PLoS ONE, 2015, v. 10, n. 9, p. 1, doi. 10.1371/journal.pone.0137311

By:

Maus, Frank;
Sakry, Dominik;
Binamé, Fabien;
Karram, Khalad;
Rajalingam, Krishnaraj;
Watts, Colin;
Heywood, Richard;
Krüger, Rejko;
Stegmüller, Judith;
Werner, Hauke B.;
Nave, Klaus-Armin;
Krämer-Albers, Eva-Maria;
Trotter, Jacqueline

Publication type:

Article

Nanobodies against the myelin enzyme CNPase as tools for structural and functional studies.

Published in:

Journal of Neurochemistry, 2025, v. 169, n. 1, p. 1, doi. 10.1111/jnc.16274

By:

Markusson, Sigurbjörn;
Raasakka, Arne;
Schröder, Marcel;
Sograte‐Idrissi, Shama;
Rahimi, Amir Mohammad;
Asadpour, Ommolbanin;
Körner, Henrike;
Lodygin, Dmitri;
Eichel‐Vogel, Maria A.;
Chowdhury, Risha;
Sutinen, Aleksi;
Muruganandam, Gopinath;
Iyer, Manasi;
Cooper, Madeline H.;
Weigel, Maya K.;
Ambiel, Nicholas;
Werner, Hauke B.;
Zuchero, J. Bradley;
Opazo, Felipe;
Kursula, Petri

Publication type:

Article

High‐affinity heterotetramer formation between the large myelin‐associated glycoprotein and the dynein light chain DYNLL1.

Published in:

Journal of Neurochemistry, 2018, v. 147, n. 6, p. 764, doi. 10.1111/jnc.14598

By:

Myllykoski, Matti;
Kursula, Petri;
Jung, Ramona B.;
Werner, Hauke B.;
Eichel, Maria A.;
Kelm, Sørge

Publication type:

Article

Functional hypoxia drives neuroplasticity and neurogenesis via brain erythropoietin.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15041-1

By:

Wakhloo, Debia;
Scharkowski, Franziska;
Curto, Yasmina;
Javed Butt, Umer;
Bansal, Vikas;
Steixner-Kumar, Agnes A.;
Wüstefeld, Liane;
Rajput, Ashish;
Arinrad, Sahab;
Zillmann, Matthias R.;
Seelbach, Anna;
Hassouna, Imam;
Schneider, Katharina;
Qadir Ibrahim, Abdul;
Werner, Hauke B.;
Martens, Henrik;
Miskowiak, Kamilla;
Wojcik, Sonja M.;
Bonn, Stefan;
Nacher, Juan

Publication type:

Article

Targeted inactivation of the Septin2 and Septin9 genes in myelinating Schwann cells of mice.

Published in:

Cytoskeleton, 2023, v. 80, n. 7/8, p. 290, doi. 10.1002/cm.21736

By:

Martens, Ann‐Kristin;
Erwig, Michelle;
Patzig, Julia;
Fledrich, Robert;
Füchtbauer, Ernst‐Martin;
Werner, Hauke B.

Publication type:

Article

Myelinating Glia-Specific Deletion of Fbxo7 in Mice Triggers Axonal Degeneration in the Central Nervous System Together with Peripheral Neuropathy.

Published in:

Journal of Neuroscience, 2019, v. 39, n. 28, p. 5606, doi. 10.1523/JNEUROSCI.3094-18.2019

By:

Joseph, Sabitha;
Vingill, Siv;
Jahn, Olaf;
Fledrich, Robert;
Werner, Hauke B.;
Katona, Istvan;
Möbius, Wiebke;
Mitkovski, Mišo;
Yuhao Huang;
Weis, Joachim;
Sereda, Michael W.;
Schulz, Jörg B.;
Nave, Klaus-Armin;
Stegmiiller, Judith

Publication type:

Article

Axonal Ensheathment in the Nervous System of Lamprey: Implications for the Evolution of Myelinating Glia.

Published in:

Journal of Neuroscience, 2018, v. 38, n. 29, p. 6586, doi. 10.1523/JNEUROSCI.1034-18.2018

By:

Weil, Marie-Theres;
Heibeck, Saskia;
Töpperwien, Mareike;
Dieck, Susanne tom;
Ruhwedel, Torben;
Salditt, Tim;
Rodicio, Maria C.;
Morgan, Jennifer R.;
Nave, Klaus-Armin;
Möbius, Wiebke;
Werner, Hauke B.

Publication type:

Article

Maintenance of high proteolipid protein level in adult central nervous system myelin is required to preserve the integrity of myelin and axons.

Published in:

Glia (0894-1491), 2019, v. 67, n. 4, p. 634, doi. 10.1002/glia.23549

By:

Lüders, Katja A.;
Nessler, Stefan;
Kusch, Kathrin;
Patzig, Julia;
Jung, Ramona B.;
Möbius, Wiebke;
Nave, Klaus‐Armin;
Werner, Hauke B.

Publication type:

Article

Glial M6B stabilizes the axonal membrane at peripheral nodes of Ranvier.

Published in:

Glia (0894-1491), 2018, v. 66, n. 4, p. 801, doi. 10.1002/glia.23285

By:

Bang, Marie L.;
Vainshtein, Anya;
Yang, Hyun‐Jeong;
Eshed‐Eisenbach, Yael;
Devaux, Jerome;
Werner, Hauke B.;
Peles, Elior

Publication type:

Article

Genetic dissection of oligodendroglial and neuronal Plp1 function in a novel mouse model of spastic paraplegia type 2.

Published in:

Glia (0894-1491), 2017, v. 65, n. 11, p. 1762, doi. 10.1002/glia.23193

By:

Lüders, Katja A.;
Patzig, Julia;
Simons, Mikael;
Nave, Klaus‐Armin;
Werner, Hauke B.

Publication type:

Article

Cortical network dysfunction caused by a subtle defect of myelination.

Published in:

Glia (0894-1491), 2016, v. 64, n. 11, p. 2025, doi. 10.1002/glia.23039

By:

Poggi, Giulia;
Boretius, Susann;
Möbius, Wiebke;
Moschny, Nicole;
Baudewig, Jürgen;
Ruhwedel, Torben;
Hassouna, Imam;
Wieser, Georg L.;
Werner, Hauke B.;
Goebbels, Sandra;
Nave, Klaus ‐ Armin;
Ehrenreich, Hannelore

Publication type:

Article

Proteolipid Protein Modulates Preservation of Peripheral Axons and Premature Death when Myelin Protein Zero is Lacking.

Published in:

Glia (0894-1491), 2016, v. 64, n. 1, p. 155, doi. 10.1002/glia.22922

By:

Patzig, Julia;
Kusch, Kathrin;
Fledrich, Robert;
Eichel, Maria A.;
Lüders, Katja A.;
Möbius, Wiebke;
Sereda, Michael W.;
Nave, Klaus‐Armin;
Martini, Rudolf;
Werner, Hauke B.

Publication type:

Article

Uncoupling of neuroinflammation from axonal degeneration in mice lacking the myelin protein tetraspanin-2.

Published in:

Glia (0894-1491), 2013, v. 61, n. 11, p. 1832, doi. 10.1002/glia.22561

By:

Monasterio‐Schrader, Patricia;
Patzig, Julia;
Möbius, Wiebke;
Barrette, Benoit;
Wagner, Tadzio L.;
Kusch, Kathrin;
Edgar, Julia M.;
Brophy, Peter J.;
Werner, Hauke B.

Publication type:

Article

Molecular evolution of myelin basic protein, an abundant structural myelin component.

Published in:

Glia (0894-1491), 2013, v. 61, n. 8, p. 1364, doi. 10.1002/glia.22520

By:

Nawaz, Schanila;
Schweitzer, Jörn;
Jahn, Olaf;
Werner, Hauke B.

Publication type:

Article

A critical role for the cholesterol-associated proteolipids PLP and M6B in myelination of the central nervous system.

Published in:

Glia (0894-1491), 2013, v. 61, n. 4, p. 567, doi. 10.1002/glia.22456

By:

Werner, Hauke B.;
Krämer‐Albers, Eva‐Maria;
Strenzke, Nicola;
Saher, Gesine;
Tenzer, Stefan;
Ohno‐Iwashita, Yoshiko;
De Monasterio‐Schrader, Patricia;
Möbius, Wiebke;
Moser, Tobias;
Griffiths, Ian R.;
Nave, Klaus‐Armin

Publication type:

Article

Early ultrastructural defects of axons and axon-glia junctions in mice lacking expression of Cnp1.

Published in:

Glia (0894-1491), 2009, v. 57, n. 16, p. 1815, doi. 10.1002/glia.20893

By:

Edgar, Julia M.;
McLaughlin, Mark;
Werner, Hauke B.;
McCulloch, Mailis C.;
Barrie, Jennifer A.;
Brown, Angus;
Faichney, Andrew Blyth;
Snaidero, Nicolas;
Nave, Klaus-Armin;
Griffiths, Ian R.

Publication type:

Article

Expression of distinct splice variants of the stem cell marker prominin-1 (CD133) in glial cells.

Published in:

Glia (0894-1491), 2009, v. 57, n. 8, p. 860, doi. 10.1002/glia.20812

By:

Corbeil, Denis;
Joester, Angret;
Fargeas, Christine A.;
Jászai, József;
Garwood, Jeremy;
Hellwig, Andrea;
Werner, Hauke B.;
Huttner, Wieland B.

Publication type:

Article

Anillin facilitates septin assembly to prevent pathological outfoldings of central nervous system myelin.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.43888.001

By:

Erwig, Michelle S.;
Patzig, Julia;
Steyer, Anna M.;
Dibaj, Payam;
Heilmann, Mareike;
Heilmann, Ingo;
Jung, Ramona B.;
Kusch, Kathrin;
Möbius, Wiebke;
Jahn, Olaf;
Nave, Klaus-Armin;
Werner, Hauke B.

Publication type:

Article

Septin/anillin filaments scaffold central nervous system myelin to accelerate nerve conduction.

Published in:

eLife, 2016, p. 1, doi. 10.7554/eLife.17119

By:

Patzig, Julia;
Erwig, Michelle S.;
Tenzer, Stefan;
Kusch, Kathrin;
Dibaj, Payam;
Möbius, Wiebke;
Goebbels, Sandra;
Schaeren-Wiemers, Nicole;
Nave, Klaus-Armin;
Werner, Hauke B.

Publication type:

Article

Systematic approaches to central nervous system myelin.

Published in:

Cellular & Molecular Life Sciences, 2012, v. 69, n. 17, p. 2879, doi. 10.1007/s00018-012-0958-9

By:

de Monasterio-Schrader, Patricia;
Jahn, Olaf;
Tenzer, Stefan;
Wichert, Sven P.;
Patzig, Julia;
Werner, Hauke B.

Publication type:

Article

Phosphatidylinositol 4,5-Bisphosphate-Dependent Interaction of Myelin Basic Protein with the Plasma Membrane in Oligodendroglial Cells and Its Rapid Perturbation by Elevated Calcium.

Published in:

Journal of Neuroscience, 2009, v. 29, n. 15, p. 4794, doi. 10.1523/JNEUROSCI.3955-08.2009

By:

Nawaz, Schanila;
Kippert, Angelika;
Saab, Aiman S.;
Werner, Hauke B.;
Lang, Thorsten;
Nave, Klaus-Armin;
Simons, Mikael

Publication type:

Article

Proteolipid Protein Is Required for Transport of Sirtuin 2 into CNS Myelin.

Published in:

Journal of Neuroscience, 2007, v. 27, n. 29, p. 7717, doi. 10.1523/JNEUROSCI.1254-07.2007

By:

Werner, Hauke B.;
Kuhlmann, Katja;
Shen, Siming;
Uecker, Marina;
Schardt, Anke;
Dimova, Kalina;
Orfaniotou, Foteini;
Dhaunchak, Ajit;
Brinkmann, Bastian G.;
Mübius, Wiebke;
Guarente, Lenny;
Casaccia-Bonnefil, Patrizia;
Jahn, Olaf;
Nave, Klaus-Armin

Publication type:

Article

Myelin matters: proteomic insights into white matter disorders.

Published in:

Expert Review of Proteomics, 2010, v. 7, n. 2, p. 159, doi. 10.1586/EPR.09.105

By:

Werner, Hauke B.;
Jahn, Olaf

Publication type:

Article

Highlight: The 5th International Workshop on Septin Biology.

Published in:

Biological Chemistry, 2014, v. 395, n. 2, p. 119, doi. 10.1515/hsz-2013-0291

By:

Mostowy, Serge;
Bi, Erfei;
Füchtbauer, Ernst-Martin;
Goryachev, Andrew B.;
Montagna, Cristina;
Nagata, Koh-ichi;
Trimble, William S.;
Werner, Hauke B.;
Yao, Xuebiao;
Zieger, Barbara;
Spiliotis, Elias T.

Publication type:

Article

Septins in the glial cells of the nervous system.

Published in:

Biological Chemistry, 2014, v. 395, n. 2, p. 143, doi. 10.1515/hsz-2013-0240

By:

Patzig, Julia;
Dworschak, Michelle S.;
Martens, Ann-Kristin;
Werner, Hauke B.

Publication type:

Article