Works matching IS 1747-0277 AND VI 91 AND IP 2 AND DT 2018

Results: 30

Nonsteroidal estrogen receptor isoform‐selective biphenyls.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 620, doi. 10.1111/cbdd.13126

By:

Bhatnagar, Seema;
Rikhi, Megha;
Kaushik, Swati;
Soni, Anjali;
Jayaram, Bhyravabhotla;
Santhoshkumar, Thankayyan Retnabai

Publication type:

Article

Peptide ligands for targeting the extracellular domain of EGFR: Comparison between linear and cyclic peptides.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 605, doi. 10.1111/cbdd.13125

By:

Williams, Tyrslai M.;
Vicente, Maria Graca H.;
Sable, Rushikesh;
Singh, Sitanshu;
Jois, Seetharama D.

Publication type:

Article

Ensemble‐based ADME–Tox profiling and virtual screening for the discovery of new inhibitors of the <italic>Leishmania mexicana</italic> cysteine protease CPB2.8ΔCTE.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 597, doi. 10.1111/cbdd.13124

By:

Scala, Angela;
Micale, Nicola;
Piperno, Anna;
Grassi, Giovanni;
Rescifina, Antonio;
Schirmeister, Tanja;
Maes, Louis

Publication type:

Article

Anticancer activity of VmCT1 analogs against MCF‐7 cells.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 588, doi. 10.1111/cbdd.13123

By:

Pedron, Cibele Nicolaski;
Andrade, Gislaine Patricia;
Sato, Roseli Hiromi;
Torres, Marcelo Der Torossian;
Cerchiaro, Giselle;
Ribeiro, Anderson Orzari;
Oliveira, Jr., Vani Xavier

Publication type:

Article

Amphiphilic small peptides for delivery of plasmid DNAs and siRNAs.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 575, doi. 10.1111/cbdd.13122

By:

Hur, Wooyoung;
Bang, Eun‐Kyoung;
Sim, Taebo;
Tran, Na Ly;
Cho, Hanna;
Jeon, Sean S.‐H.;
Lim, Dong‐Kwon

Publication type:

Article

Design of potent B‐RafV600E inhibitors by multiple copy simulation search strategy.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 567, doi. 10.1111/cbdd.13121

By:

Wang, Ze‐Feng;
Wang, Peng‐Fei;
Ma, Jun‐Ting;
Chai, Ying‐Zi;
Hu, Hui‐Min;
Gao, Wen‐Long;
Wang, Zhong‐Chang;
Wang, Bao‐Zhong;
Zhu, Hai‐Liang

Publication type:

Article

Design, synthesis, and cytotoxic evaluation of novel scopoletin derivatives.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 641, doi. 10.1111/cbdd.13120

By:

Shi, Wei;
Zhang, Jinlu;
Bao, Na;
Chen, Li;
Sun, Jianbo;
Guan, Fuqin

Publication type:

Article

Selective inhibition of TRPM2 channel by two novel synthesized ADPR analogues.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 552, doi. 10.1111/cbdd.13119

By:

Luo, Xiao;
Zhang, Lihe;
Zhang, Liangren;
Li, Meng;
Wang, KeWei;
Zhan, Kaiyu;
Yang, Wei;
Yu, Peilin

Publication type:

Article

Synthesis and evaluation of a novel 99mTc nitrido radiopharmaceutical with alendronate dithiocarbamate as a potential bone‐imaging agent.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 545, doi. 10.1111/cbdd.13117

By:

Song, Xiaoqing;
Wang, Yue;
Zhang, Junbo;
Jin, Zhonghui;
Zhang, Weifang;
Zhang, Yanyan

Publication type:

Article

Legumain correlates with neuroblastoma differentiation and can be used in prodrug design.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 534, doi. 10.1111/cbdd.13116

By:

Zhang, Min;
Jiang, Zhiteng;
Chen, Sheng;
Wu, Zhixiang;
Chen, Kai;
Wu, Yeming

Publication type:

Article

Peptide Bond Formations through Flow Chemistry.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 647, doi. 10.1111/cbdd.13115

By:

Ahmed, Nisar

Publication type:

Article

Design, synthesis, and biological evaluation of 5‐(4‐(pyridin‐4‐yl)‐1<italic>H</italic>‐1,2,3‐triazol‐1‐yl)benzonitrile derivatives as xanthine oxidase inhibitors.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 526, doi. 10.1111/cbdd.13114

By:

Zhang, Ting‐jian;
Li, Song‐ye;
Zhang, Yi;
Wu, Qing‐xia;
Meng, Fan‐hao

Publication type:

Article

Molecular modeling studies of pseudouridine isoxazolidinyl nucleoside analogues as potential inhibitors of the pseudouridine 5ʹ‐monophosphate glycosidase.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 519, doi. 10.1111/cbdd.13113

By:

Pistarà, Venerando;
Amata, Emanuele;
Dichiara, Maria;
Damigella, Arcangelo;
Marrazzo, Agostino;
Prezzavento, Orazio;
Punzo, Francesco;
Rescifina, Antonio;
Floresta, Giuseppe

Publication type:

Article

Potential biological targets for bioassay development in drug discovery of Sturge–Weber syndrome.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 359, doi. 10.1111/cbdd.13112

By:

Mohammadipanah, Fatemeh;
Salimi, Fatemeh

Publication type:

Article

Novel tetrahydroacridine derivatives with iodobenzoic acid moiety as multifunctional acetylcholinesterase inhibitors.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 505, doi. 10.1111/cbdd.13111

By:

Skibiński, Robert;
Czarnecka, Kamila;
Girek, Małgorzata;
Bilichowski, Ireneusz;
Chufarova, Nina;
Mikiciuk‐Olasik, Elżbieta;
Szymański, Paweł

Publication type:

Article

Ensemble docking to difficult targets in early‐stage drug discovery: Methodology and application to fibroblast growth factor 23.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 491, doi. 10.1111/cbdd.13110

By:

Velazquez, Hector A.;
Baudry, Jerome;
Smith, Jeremy C.;
Riccardi, Demian;
Xiao, Zhousheng;
Quarles, Leigh Darryl;
Yates, Charless Ryan

Publication type:

Article

Pharmacophore‐based virtual screening, molecular docking, molecular dynamics simulation, and biological evaluation for the discovery of novel BRD4 inhibitors.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 478, doi. 10.1111/cbdd.13109

By:

Yan, Guoyi;
Hou, Manzhou;
Luo, Jiang;
Pu, Chunlan;
Hou, Xueyan;
Lan, Suke;
Li, Rui

Publication type:

Article

New insights into the mechanism of action of pyrazolo[1,2‐a]benzo[1,2,3,4]tetrazin‐3‐one derivatives endowed with anticancer potential.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 463, doi. 10.1111/cbdd.13108

By:

Lauria, Antonino;
Delisi, Riccardo;
Martorana, Annamaria;
Mingoia, Francesco;
Dalla Via, Lisa;
García‐Argáez, Aída Nelly

Publication type:

Article

Synthesis, quality control, and bio‐evaluation of 99mTc‐cyclophosphamide.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 456, doi. 10.1111/cbdd.13107

By:

Bokhari, Tanveer Hussain;
Akbar, Muhammad Usman;
Roohi, Samina;
Hina, Saira;
Sohaib, Muhammad;
Iqbal, Munawar

Publication type:

Article

Structural properties of bioactive peptides with α‐glucosidase inhibitory activity.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 370, doi. 10.1111/cbdd.13105

By:

Neitz, Albert W. H.;
Gaspar, Anabella R. M.;
Ibrahim, Mohammed Auwal;
Bester, Megan J.

Publication type:

Article

Expression in <italic>Escherichia coli</italic> of fusion protein comprising α‐conotoxin TxIB and preservation of selectivity to nicotinic acetylcholine receptors in the purified product.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 349, doi. 10.1111/cbdd.13104

By:

Zhu, Xiaopeng;
Luo, Sulan;
Zhangsun, Dongting;
Yu, Jinpeng;
Yang, Yang

Publication type:

Article

Issue Information.

Published in:: 2018
Publication type:: Table of Contents

Sofosbuvir as treatment against dengue?

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 448, doi. 10.1111/cbdd.13091

By:

Gan, Chye Sheng;
Heh, Choon Han;
Chee, Chin Fei;
Yusof, Rohana;
Lim, See Khai

Publication type:

Article

Synthesis, enzyme inhibitory kinetics, and computational studies of novel 1‐(2‐(4‐isobutylphenyl) propanoyl)‐3‐arylthioureas as Jack bean urease inhibitors.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 434, doi. 10.1111/cbdd.13090

By:

Abdul Fattah, Tanzeela;
Saeed, Aamer;
Channar, Pervaiz Ali;
Larik, Fayaz Ali;
Ashraf, Zaman;
Abbas, Qamar;
Hassan, Mubashir

Publication type:

Article

Bitter substances from plants used in traditional Chinese medicine exert biased activation of human bitter taste receptors.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 422, doi. 10.1111/cbdd.13089

By:

Behrens, Maik;
Meyerhof, Wolfgang;
Gu, Ming;
Fan, Shengjie;
Huang, Cheng

Publication type:

Article

Lipophilic conformationally constrained spiro carbocyclic 2,6‐diketopiperazine‐1‐acetohydroxamic acid analogues as trypanocidal and leishmanicidal agents: An extended SAR study.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 408, doi. 10.1111/cbdd.13088

By:

Zoidis, Grigoris;
Tsotinis, Andrew;
Tsatsaroni, Alexandra;
Fytas, George;
Taylor, Martin C.;
Kelly, John M.;
Efstathiou, Antonia;
Smirlis, Despina

Publication type:

Article

Synthesis and in vitro investigation of halogenated 1,3‐bis(4‐nitrophenyl)triazenide salts as antitubercular compounds.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 631, doi. 10.1111/cbdd.13087

By:

Torfs, Eveline;
de Macedo, Maíra Bidart;
Cools, Freya;
Vanhoutte, Bieke;
Caljon, Guy;
Maes, Louis;
Delputte, Peter;
Cos, Paul;
Cappoen, Davie;
Vajs, Jure;
Košmrlj, Janez;
Gorbanev, Yury;
Bogaerts, Annemie;
Verschaeve, Luc

Publication type:

Article

Docking field‐based QSAR and pharmacophore studies on the substituted pyrimidine derivatives targeting HIV‐1 reverse transcriptase.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 398, doi. 10.1111/cbdd.13086

By:

Fan, Ningning;
Sheng, Tao;
Wang, Xiaowei;
Liu, Junyi;
Zhang, Shuang;
Zhao, Liang;
Liu, Zhenming

Publication type:

Article

Discovery of naphthyl‐<italic>N</italic>‐acylhydrazone p38α MAPK inhibitors with in vivo anti‐inflammatory and anti‐TNF‐α activity.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 391, doi. 10.1111/cbdd.13085

By:

Freitas, Rosana H. C. N.;
Alves, Marina A.;
Lima, Lídia M.;
Barreiro, Eliezer J.;
Fraga, Carlos A. M.;
Cordeiro, Natália M.;
Carvalho, Patrícia R.;
Valerio, Tayna S.;
Fernandes, Patrícia D.;
Guedes, Isabella A.;
Dardenne, Laurent E.

Publication type:

Article

Aromatic interactions at the ligand–protein interface: Implications for the development of docking scoring functions.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 380, doi. 10.1111/cbdd.13084

By:

Brylinski, Michal

Publication type:

Article

Works matching IS 1747-0277 AND VI 91 AND IP 2 AND DT 2018

Nonsteroidal estrogen receptor isoform‐selective biphenyls.

Peptide ligands for targeting the extracellular domain of EGFR: Comparison between linear and cyclic peptides.

Ensemble‐based ADME–Tox profiling and virtual screening for the discovery of new inhibitors of the <italic>Leishmania mexicana</italic> cysteine protease CPB2.8ΔCTE.

Anticancer activity of VmCT1 analogs against MCF‐7 cells.

Amphiphilic small peptides for delivery of plasmid DNAs and siRNAs.

Design of potent B‐Raf<sup>V600E</sup> inhibitors by multiple copy simulation search strategy.

Design, synthesis, and cytotoxic evaluation of novel scopoletin derivatives.

Selective inhibition of TRPM2 channel by two novel synthesized ADPR analogues.

Synthesis and evaluation of a novel <sup>99m</sup>Tc nitrido radiopharmaceutical with alendronate dithiocarbamate as a potential bone‐imaging agent.

Legumain correlates with neuroblastoma differentiation and can be used in prodrug design.

Peptide Bond Formations through Flow Chemistry.

Design, synthesis, and biological evaluation of 5‐(4‐(pyridin‐4‐yl)‐1<italic>H</italic>‐1,2,3‐triazol‐1‐yl)benzonitrile derivatives as xanthine oxidase inhibitors.

Molecular modeling studies of pseudouridine isoxazolidinyl nucleoside analogues as potential inhibitors of the pseudouridine 5ʹ‐monophosphate glycosidase.

Potential biological targets for bioassay development in drug discovery of Sturge–Weber syndrome.

Novel tetrahydroacridine derivatives with iodobenzoic acid moiety as multifunctional acetylcholinesterase inhibitors.

Ensemble docking to difficult targets in early‐stage drug discovery: Methodology and application to fibroblast growth factor 23.

Pharmacophore‐based virtual screening, molecular docking, molecular dynamics simulation, and biological evaluation for the discovery of novel BRD4 inhibitors.

New insights into the mechanism of action of pyrazolo[1,2‐a]benzo[1,2,3,4]tetrazin‐3‐one derivatives endowed with anticancer potential.

Synthesis, quality control, and bio‐evaluation of <sup>99m</sup>Tc‐cyclophosphamide.

Structural properties of bioactive peptides with α‐glucosidase inhibitory activity.

Expression in <italic>Escherichia coli</italic> of fusion protein comprising α‐conotoxin TxIB and preservation of selectivity to nicotinic acetylcholine receptors in the purified product.

Issue Information.

Sofosbuvir as treatment against dengue?

Synthesis, enzyme inhibitory kinetics, and computational studies of novel 1‐(2‐(4‐isobutylphenyl) propanoyl)‐3‐arylthioureas as Jack bean urease inhibitors.

Bitter substances from plants used in traditional Chinese medicine exert biased activation of human bitter taste receptors.

Lipophilic conformationally constrained spiro carbocyclic 2,6‐diketopiperazine‐1‐acetohydroxamic acid analogues as trypanocidal and leishmanicidal agents: An extended SAR study.

Synthesis and in vitro investigation of halogenated 1,3‐bis(4‐nitrophenyl)triazenide salts as antitubercular compounds.

Docking field‐based QSAR and pharmacophore studies on the substituted pyrimidine derivatives targeting HIV‐1 reverse transcriptase.

Discovery of naphthyl‐<italic>N</italic>‐acylhydrazone p38α MAPK inhibitors with in vivo anti‐inflammatory and anti‐TNF‐α activity.

Aromatic interactions at the ligand–protein interface: Implications for the development of docking scoring functions.