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A High Threshold of Biotherapeutic Aggregate Numbers is Needed to Induce an Immunogenic Response In Vitro, In Vivo, and in the Clinic.
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- Pharmaceutical Research, 2024, v. 41, n. 4, p. 651, doi. 10.1007/s11095-024-03678-2
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- Article
Multiple Conformational States of a New Hematopoietic Cytokine (Megakaryocyte Growth and Development Factor): pH- and Urea-Induced Denaturation
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- Proteins, 1998, v. 32, n. 4, p. 495
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- Article
Effect of the intermolecular disulfide bond on the conformation and stability of glial cell line-derived neurotrophic factor.
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- Protein Engineering, 2002, v. 15, n. 1, p. 59, doi. 10.1093/protein/15.1.59
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- Article
Asn to Lys mutations at three sites which are N-glycosylated in the mammalian protein decrease the aggregation of Escherichia coli-derived erythropoietin.
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- Protein Engineering, 2001, v. 14, n. 2, p. 135, doi. 10.1093/protein/14.2.135
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- Article
Use of In Vitro Assays to Assess Immunogenicity Risk of Antibody-Based Biotherapeutics.
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- PLoS ONE, 2016, v. 11, n. 8, p. 1, doi. 10.1371/journal.pone.0159328
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- Article
Ion-specific modulation of protein interactions: Anion-induced, reversible oligomerization of a fusion protein.
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- Protein Science: A Publication of the Protein Society, 2009, v. 18, n. 1, p. 169, doi. 10.1002/pro.20
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- Article
Enhanced stability of recombinant keratinocyte growth factor by mutagenesis.
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- PEDS: Protein Engineering, Design & Selection, 2006, v. 19, n. 4, p. 147, doi. 10.1093/protein/gzj013
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- Article