Works matching AU Jaochico, Allan

Results: 7

NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02672-0

By:

Brightbill, Hans D.;
Suto, Eric;
Blaquiere, Nicole;
Sujatha-Bhaskar, Swathi;
Gogol, Emily B.;
Castanedo, Georgette M.;
Jackson, Benjamin T.;
Kwon, Youngsu C.;
Haller, Susan;
Lesch, Justin;
Bents, Karin;
Everett, Christine;
Kohli, Pawan Bir;
Linge, Sandra;
Christian, Laura;
Barrett, Kathy;
Jaochico, Allan;
Berezhkovskiy, Leonid M.;
Fan, Peter W.;
Modrusan, Zora

Publication type:

Article

Glycochenodeoxycholate and glycodeoxycholate 3‐O‐glucuronides, but not hexadecanedioate and tetradecanedioate, detected weak inhibition of OATP1B caused by GDC‐0810 in humans.

Published in:

British Journal of Clinical Pharmacology, 2023, v. 89, n. 6, p. 1903, doi. 10.1111/bcp.15679

By:

Yoshida, Kenta;
Jaochico, Allan;
Mao, Jialin;
Sangaraju, Dewakar

Publication type:

Article

In vitro and in vivo characterization of CYP inhibition by 1-aminobenzotriazole in rats.

Published in:

Biopharmaceutics & Drug Disposition, 2016, v. 37, n. 4, p. 200, doi. 10.1002/bdd.2000

By:

Parrish, Karen E.;
Mao, Jialin;
Chen, Jacob;
Jaochico, Allan;
Ly, Justin;
Ho, Quynh;
Mukadam, Sophie;
Wright, Matthew

Publication type:

Article

Inhibition of the kinase ITK in a mouse model of asthma reduces cell death and fails to inhibit the inflammatory response.

Published in:

Science Signaling, 2015, v. 8, n. 405, p. 1, doi. 10.1126/scisignal.aab0949

By:

Yonglian Sun;
Peng, Ivan;
Webster, Joshua D.;
Suto, Eric;
Lesch, Justin;
Xiumin Wu;
Senger, Kate;
Francis, George;
Barrett, Kathy;
Collier, Jenna L.;
Burch, Jason D.;
Meijuan Zhou;
Yuan Chen;
Connie Chan;
Eastham-Anderson, Jeff;
Hai Ngu;
Li, Olga;
Staton, Tracy;
Havnar, Charles;
Jaochico, Allan

Publication type:

Article

Preclinical assessment of the PI3Kα selective inhibitor inavolisib and prediction of its pharmacokinetics and efficacious dose in human.

Published in:

Xenobiotica, 2024, v. 54, n. 10, p. 808, doi. 10.1080/00498254.2024.2415103

By:

Salphati, Laurent;
Pang, Jodie;
Plise, Emile G.;
Cheong, Jonathan;
Braun, Marie-Gabrielle;
Friedman, Lori S.;
Hong Thibodeau, Rebecca;
Jaochico, Allan;
Johnson, Ryan;
Liu, Ning;
Nannini, Michelle;
Sampath, Deepak;
Song, Kyung;
Hannan, Emily J.;
Staben, Steven T.

Publication type:

Article

Preclinical characterization of the absorption and disposition of the brain penetrant PI3K/mTOR inhibitor paxalisib and prediction of its pharmacokinetics and efficacy in human.

Published in:

Xenobiotica, 2024, v. 54, n. 2, p. 64, doi. 10.1080/00498254.2024.2303586

By:

Salphati, Laurent;
Pang, Jodie;
Alicke, Bruno;
Plise, Emile G.;
Cheong, Jonathan;
Jaochico, Allan;
Olivero, Alan G.;
Sampath, Deepak;
Wong, Susan;
Zhang, Xiaolin

Publication type:

Article

High-throughput liquid chromatography/mass spectrometry method for the quantitation of small molecules using accurate mass technologies in supporting discovery drug screening.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2013, v. 27, n. 3, p. 401, doi. 10.1002/rcm.6461

By:

Ding, Xiao;
Ghobarah, Hesham;
Zhang, Xiaolin;
Jaochico, Allan;
Liu, Xingrong;
Deshmukh, Gauri;
Liederer, Bianca M.;
Hop, Cornelis E. C. A.;
Dean, Brian

Publication type:

Article