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Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29552-6
By:
- Wang, Chao;
- Fan, Li;
- Khawaja, Rabia R.;
- Liu, Bangyan;
- Zhan, Lihong;
- Kodama, Lay;
- Chin, Marcus;
- Li, Yaqiao;
- Le, David;
- Zhou, Yungui;
- Condello, Carlo;
- Grinberg, Lea T.;
- Seeley, William W.;
- Miller, Bruce L.;
- Mok, Sue-Ann;
- Gestwicki, Jason E.;
- Cuervo, Ana Maria;
- Luo, Wenjie;
- Gan, Li
Publication type:
Article
Bioinformatics Analysis of Publicly Available Single-Nuclei Transcriptomics Alzheimer's Disease Datasets Reveals APOE Genotype-Specific Changes Across Cell Types in Two Brain Regions.
Published in:
Frontiers in Aging Neuroscience, 2022, v. 14, p. 1, doi. 10.3389/fnagi.2022.749991
By:
- Belonwu, Stella A.;
- Li, Yaqiao;
- Bunis, Daniel G.;
- Rao, Arjun Arkal;
- Solsberg, Caroline Warly;
- Oskotsky, Tomiko;
- Taubes, Alice L.;
- Grone, Brian;
- Zalocusky, Kelly A.;
- Fragiadakis, Gabriela K.;
- Huang, Yadong;
- Sirota, Marina
Publication type:
Article
Predictive Modeling Leveraging Electronic Health Records Identifies Early Predictors of Alzheimer's Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077061
By:
- Tang, Alice S;
- Rankin, Katherine P;
- Cerano, Gabriel;
- Miramontes, Silvia;
- Mills, Hunter;
- Oskotsky, Tomiko;
- Zeng, Billy;
- Nelson, Charlotte;
- Soman, Karthik;
- Woldemariam, Sarah;
- Li, Yaqiao;
- Lee, Albert M;
- Miller, Zachary;
- Allen, Isabel Elaine;
- Sanders, Stephan;
- Baranzini, Sergio;
- Sirota, Marina
Publication type:
Article
Transcriptomic Profiling Across Age, APOE and Sex for Models of Alzheimer's Disease at a Single Cell Resolution.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080132
By:
- Li, Yaqiao;
- Hao, Yanxia;
- Yoon, Seo Yeon;
- Grone, Brian;
- Ding, Leonardo;
- Blumenfeld, Jessica;
- Oskotsky, Tomiko;
- Huang, Yadong;
- Sirota, Marina
Publication type:
Article
Effect of KIBRA on tau‐mediated synaptic and memory deficits.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.053394
By:
- Kauwe, Grant;
- Pareja‐Navarro, Kristeen;
- Chen, Jackson;
- Li, Yaqiao;
- Le, David;
- Zhou, Yungui;
- Gan, Li;
- Tracy, Tara E
Publication type:
Article
P4‐511: A NOVEL ROLE FOR THE FTD‐CAUSING PROTEIN PROGRANULIN IN APOPTOSIS SIGNALING.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1509, doi. 10.1016/j.jalz.2019.08.057
By:
- Clelland, Claire;
- Etchegaray, J. Iker;
- Kodama, Lay;
- Sayed, Faten;
- Sachdev, Aradhana;
- Li, Yaqiao;
- Le, David;
- Zhan, Lihong;
- Zhou, Yungui;
- Duong, Duc;
- Seyfried, Nicholas T.;
- Kukar, Thomas G.;
- Tan, Li Xuan;
- Lakkaraju, Aparna;
- Conklin, Bruce;
- Gan, Li
Publication type:
Article
The REST Gene Signature Predicts Drug Sensitivity in Neuroblastoma Cell Lines and Is Significantly Associated with Neuroblastoma Tumor Stage.
Published in:
International Journal of Molecular Sciences, 2014, v. 15, n. 7, p. 11220, doi. 10.3390/ijms150711220
By:
- Jianfeng Liang;
- Pan Tong;
- Wanni Zhao;
- Yaqiao Li;
- Li Zhang;
- Ying Xia;
- Yanbing Yu
Publication type:
Article
Optimization of Control Loops and Operating Parameters for Three-Phase Separators Used in Oilfield Central Processing Facilities.
Published in:
Fluid Dynamics & Materials Processing, 2023, v. 19, n. 3, p. 635, doi. 10.32604/fdmp.2022.020633
By:
- Zhenfeng Li;
- Yaqiao Li;
- Guangjun Wei
Publication type:
Article
A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain.
Published in:
eLife, 2020, p. 1, doi. 10.7554/eLife.51796
By:
- Lihong Zhan;
- Li Fan;
- Kodama, Lay;
- Sohn, Peter Dongmin;
- Man Ying Wong;
- Mousa, Gergey Alzaem;
- Yungui Zhou;
- Yaqiao Li;
- Li Gan
Publication type:
Article
Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.
Published in:
Nature Medicine, 2015, v. 21, n. 10, p. 1154, doi. 10.1038/nm.3951
By:
- Min, Sang-Won;
- Chen, Xu;
- Tracy, Tara E;
- Li, Yaqiao;
- Zhou, Yungui;
- Wang, Chao;
- Shirakawa, Kotaro;
- Minami, S Sakura;
- Defensor, Erwin;
- Mok, Sue Ann;
- Sohn, Peter Dongmin;
- Schilling, Birgit;
- Cong, Xin;
- Ellerby, Lisa;
- Gibson, Bradford W;
- Johnson, Jeffrey;
- Krogan, Nevan;
- Shamloo, Mehrdad;
- Gestwicki, Jason;
- Masliah, Eliezer
Publication type:
Article
Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models.
Published in:
Nature Medicine, 2014, v. 20, n. 10, p. 1157, doi. 10.1038/nm.3672
By:
- Minami, S Sakura;
- Min, Sang-Won;
- Krabbe, Grietje;
- Wang, Chao;
- Zhou, Yungui;
- Asgarov, Rustam;
- Li, Yaqiao;
- Martens, Lauren H;
- Elia, Lisa P;
- Ward, Michael E;
- Mucke, Lennart;
- Farese, Robert V;
- Gan, Li
Publication type:
Article
Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2014, v. 10, p. P146, doi. 10.1016/j.jalz.2014.04.102
By:
- Gan, Li;
- Min, Sang-Won;
- Tracy, Tara;
- Chen, Xu;
- Sohn, Peter;
- Wang, Chao;
- Minami, Sakura;
- Zhou, Yungui;
- Yaqiao, Li
Publication type:
Article
Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain.
Published in:
PLoS Biology, 2019, v. 17, n. 2, p. 1, doi. 10.1371/journal.pbio.3000134
By:
- Zhan, Lihong;
- Krabbe, Grietje;
- Du, Fei;
- Jones, Ian;
- Reichert, Meredith C.;
- Telpoukhovskaia, Maria;
- Kodama, Lay;
- Wang, Chao;
- Cho, Seo-hyun;
- Sayed, Faten;
- Li, Yaqiao;
- Le, David;
- Zhou, Yungui;
- Shen, Yin;
- West, Brian;
- Gan, Li
Publication type:
Article
Correction: OTG-snpcaller: An Optimized Pipeline Based on TMAP and GATK for SNP Calling from Ion Torrent Data.
Published in:
PLoS ONE, 2015, v. 10, n. 9, p. 1, doi. 10.1371/journal.pone.0138824
By:
- Zhu, Pengyuan;
- He, Lingyu;
- Li, Yaqiao;
- Huang, Wenpan;
- Xi, Feng;
- Lin, Lin;
- Zhi, Qihuan;
- Zhang, Wenwei;
- Tang, Y. Tom;
- Geng, Chunyu;
- Lu, Zhiyuan;
- Xu, Xun
Publication type:
Article
OTG-snpcaller: An Optimized Pipeline Based on TMAP and GATK for SNP Calling from Ion Torrent Data.
Published in:
PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0097507
By:
- Zhu, Pengyuan;
- He, Lingyu;
- Li, Yaqiao;
- Huang, Wenpan;
- Xi, Feng;
- Lin, Lin;
- Zhi, Qihuan;
- Zhang, Wenwei;
- Tang, Y. Tom;
- Geng, Chunyu;
- Lu, Zhiyuan;
- Xu, Xun
Publication type:
Article
Impact of the amount of PEG on prodrug nanoassemblies for efficient cancer therapy.
Published in:
Asian Journal of Pharmaceutical Sciences, 2022, v. 17, n. 2, p. 241, doi. 10.1016/j.ajps.2022.02.002
By:
- Yaqiao Li;
- Lingxiao Li;
- Qianhui Jin;
- Tian Liu;
- Jin Sun;
- Yongjun Wang;
- Zhijun Yang;
- Zhonggui He;
- Bingjun Sun
Publication type:
Article
Small‐Molecule Prodrug Nanoassemblies: An Emerging Nanoplatform for Anticancer Drug Delivery.
Published in:
Small, 2021, v. 17, n. 52, p. 1, doi. 10.1002/smll.202101460
By:
- Li, Guanting;
- Sun, Bingjun;
- Li, Yaqiao;
- Luo, Cong;
- He, Zhonggui;
- Sun, Jin
Publication type:
Article
Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-70534-9
By:
- Telpoukhovskaia, Maria A.;
- Liu, Kai;
- Sayed, Faten A.;
- Etchegaray, Jon Iker;
- Xie, Min;
- Zhan, Lihong;
- Li, Yaqiao;
- Zhou, Yungui;
- Le, David;
- Bahr, Ben A.;
- Bogyo, Matthew;
- Ding, Sheng;
- Gan, Li
Publication type:
Article
SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy.
Published in:
Journal of Neuroscience, 2018, v. 38, n. 15, p. 3680, doi. 10.1523/JNEUROSCI.2369-17.2018
By:
- Sang-Won Min;
- Dongmin Sohn, Peter;
- Yaqiao Li;
- Devidze, Nino;
- Johnson, Jeffrey R.;
- Krogan, Nevan J.;
- Masliah, Eliezer;
- Sue-Ann Mok;
- Gestwicki, Jason E.;
- Li Gan
Publication type:
Article
Anti-acetylated-tau immunotherapy is neuroprotective in tauopathy and brain injury.
Published in:
Molecular Neurodegeneration, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13024-024-00733-9
By:
- Parra Bravo, Celeste;
- Krukowski, Karen;
- Barker, Sarah;
- Wang, Chao;
- Li, Yaqiao;
- Fan, Li;
- Vázquez-Rosa, Edwin;
- Shin, Min-Kyoo;
- Wong, Man Ying;
- McCullough, Louise D.;
- Kitagawa, Ryan S.;
- Choi, H. Alex;
- Cacace, Angela;
- Sinha, Subhash C.;
- Pieper, Andrew A.;
- Rosi, Susanna;
- Chen, Xu;
- Gan, Li
Publication type:
Article
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury.
Published in:
Nature Chemical Biology, 2013, v. 9, n. 3, p. 192, doi. 10.1038/nchembio0313-192a
By:
- Degterev, Alexei;
- Huang, Zhihong;
- Boyce, Michael;
- Li, Yaqiao;
- Jagtap, Prakash;
- Mizushima, Noboru;
- Cuny, Gregory D;
- Mitchison, Timothy J;
- Moskowitz, Michael A;
- Yuan, Junying
Publication type:
Article
Corrigendum: Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury.
Published in:
2005
By:
- Degterev, Alexei;
- Zhihong Huang;
- Boyce, Michael;
- Yaqiao Li;
- Jagtap, Prakash;
- Mizushima, Noboru;
- Cuny, Gregory D.;
- Mitchison, Timothy J.;
- Moskowitz, Michael A.;
- Junying Yuan
Publication type:
Correction Notice
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury.
Published in:
Nature Chemical Biology, 2005, v. 1, n. 2, p. 112, doi. 10.1038/nchembio711
By:
- Degterev, Alexei;
- Zhihong Huang;
- Boyce, Michael;
- Yaqiao Li;
- Jagtap, Prakash;
- Noboru Mizushima;
- Cuny, Gregory D.;
- Mitchison, Timothy J.;
- Moskowitz, Michael A.;
- Junying Yuan
Publication type:
Article
Sex-Stratified Single-Cell RNA-Seq Analysis Identifies Sex-Specific and Cell Type-Specific Transcriptional Responses in Alzheimer's Disease Across Two Brain Regions.
Published in:
Molecular Neurobiology, 2022, v. 59, n. 1, p. 276, doi. 10.1007/s12035-021-02591-8
By:
- Belonwu, Stella A.;
- Li, Yaqiao;
- Bunis, Daniel;
- Rao, Arjun Arkal;
- Solsberg, Caroline Warly;
- Tang, Alice;
- Fragiadakis, Gabriela K.;
- Dubal, Dena B.;
- Oskotsky, Tomiko;
- Sirota, Marina
Publication type:
Article
Satellite‐Type Sulfur Atom Distribution in Trithiocarbonate Bond‐Bridged Dimeric Prodrug Nanoassemblies: Achieving Both Stability and Activatability.
Published in:
Advanced Materials, 2024, v. 36, n. 4, p. 1, doi. 10.1002/adma.202310633
By:
- Li, Lingxiao;
- Liu, Tian;
- Zuo, Shiyi;
- Li, Yaqiao;
- Zhao, Erwei;
- Lu, Qi;
- Wang, Danping;
- Sun, Yixin;
- He, Zhonggui;
- Sun, Bingjun;
- Sun, Jin
Publication type:
Article
Erratum to: Balancing efficacy and safety of doxorubicin-loaded albumin nanoparticles utilizing pH-sensitive doxorubicin-fatty acid prodrugs.
Published in:
2024
By:
- Yu, Yuanhao;
- Zuo, Shiyi;
- Song, Jiaxuan;
- Li, Lingxiao;
- Liu, Tian;
- Guo, Jiayu;
- Li, Yaqiao;
- Wang, Danping;
- Lu, Qi;
- Wang, Helin;
- Zhou, Dun;
- He, Zhonggui;
- Liu, Xiaohong;
- Sun, Bingjun;
- Sun, Jin
Publication type:
Correction Notice
Balancing efficacy and safety of doxorubicin-loaded albumin nanoparticles utilizing pH-sensitive doxorubicin-fatty acid prodrugs.
Published in:
Nano Research, 2024, v. 17, n. 6, p. 5491, doi. 10.1007/s12274-024-6533-5
By:
- Yu, Yuanhao;
- Zuo, Shiyi;
- Song, Jiaxuan;
- Li, Lingxiao;
- Liu, Tian;
- Guo, Jiayu;
- Li, Yaqiao;
- Wang, Danping;
- Lu, Qi;
- Wang, Helin;
- Zhou, Dun;
- He, Zhonggui;
- Liu, Xiaohong;
- Sun, Bingjun;
- Sun, Jin
Publication type:
Article
Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy.
Published in:
Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-019-0354-0
By:
- Chen, Xu;
- Li, Yaqiao;
- Wang, Chao;
- Tang, Yinyan;
- Mok, Sue-Ann;
- Tsai, Richard M.;
- Rojas, Julio C.;
- Karydas, Anna;
- Miller, Bruce L.;
- Boxer, Adam L.;
- Gestwicki, Jason E.;
- Arkin, Michelle;
- Cuervo, Ana Maria;
- Gan, Li
Publication type:
Article

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