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- Title
Associated factors with recurrent wheezing in infants: is there difference between the sexes?
- Authors
da Silva Ferreira, Wellington Fernando; Siqueira de Carvalho, Denise; Falbo Wandalsen, Gustavo; Solé, Dirceu; Cavalcante Sarinho, Emanuel Sávio; Med, Décio; Cavalcanti Dela Bianca Melo, Ana Carolina; Xavier Prestes, Elaine; Moreira Camargos, Paulo Augusto; Regina Luhm, Karin; Garcia-Marcos, Luis; Mallol, Javier; Augusto Rosário, Nelson; José Chong-Neto, Herberto
- Abstract
Objective: Identify associated factors for recurrent wheezing (RW) in male and female infants. Methods: Cross-sectional multicentric study using the standardized questionnaire from the Estudio Internacional sobre Sibilancias en Lactantes (EISL). The questionnaire was applied to parents of 9345 infants aged 12--15 months at the time of immunization/routine visits. Results: One thousand two hundred and sixty-one (13.5%) males and nine hundred sixty-three (10.3%) females have had RW (=3 episodes), respectively (p10 colds episodes (OR = 3.46; IC 95% 2.35--5.07), air pollution (OR = 1.33; IC 95% 1.12--1.59), molds at home (OR = 1.23; IC 95% 1.03--1.47), Afro-descendants (OR = 1.42; IC 95% 1.20--1.69), bronchopneumonia (OR = 1.41; IC; 1.11--1.78), severe episodes of wheezing in the first year (OR = 1.56; IC 95% 1.29--1.89), treatment with bronchodilators (OR = 1.60; IC 95% 1.22--2,1) and treatment with oral corticosteroids (OR = 1,23; IC 95% 0.99--1,52). Associated factors for RW for females were passive smoking (OR = 1.24; IC 95% 1.01-1,51), parents diagnosed with asthma (OR = 1.32; IC 95% 1,08-1,62), parents with allergic rhinitis (OR = 1.26; IC 95% 1.04--1.53), daycare attendance (OR = 1.48; IC 95% 1.17-1,88), colds in the first 6 months of life (OR = 2.19; IC 95% 1.69--2.82), personal diagnosis of asthma (OR = 1.84; IC 95% 1.39--2.44), emergency room visits (OR = 1.78; IC 95% 1.44--2.21), nighttime symptoms (OR = 2.89; IC 95% 2.34--3.53) and updated immunization (OR = 0.62; IC 95% 0.41-0.96). Conclusion: There are differences in associated factors for RW between genders. Identification of these differences could be useful to the approach and management of RW between boys and girls.
- Subjects
WHEEZE; NEWBORN infants; IMMUNIZATION; CORTICOSTEROIDS; BRONCHODILATOR agents; GENDER differences (Psychology)
- Publication
Jornal de Pediatria, 2021, Vol 97, Issue 6, p629
- ISSN
0021-7557
- Publication type
Article
- DOI
10.1016/j.jped.2021.01.001