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- Title
Fatal outcome of herpes simplex virus type 1-induced necrotic hepatitis in a neonate.
- Authors
Meerbach, Astrid; Sauerbrei, Andreas; Meerbach, Werner; Bittrich, Hans-Jörg; Wutzler, Peter
- Abstract
In neonates, herpes simplex virus (HSV) infections can lead to severe diseases associated with high mortality. We report a 6-day-old girl who developed clinical signs of fulminant hepatic failure accompanied by infectious-toxic shock and disseminated coagulopathy secondary to HSV type 1 (HSV-1) infection. The diagnosis was performed postmortem by demonstration of HSV-1 DNA in liver tissue as well as by retrospective detection of HSV-specific antibodies.
- Subjects
HERPES simplex virus; NEWBORN infants; LIVER failure; HEPATITIS; BRAXY; IMMUNOGLOBULINS
- Publication
Medical Microbiology & Immunology, 2006, Vol 195, Issue 2, p101
- ISSN
0300-8584
- Publication type
Article
- DOI
10.1007/s00430-005-0009-3