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Telomere length homeostasis requires that telomerase levels are limiting.
- Published in:
- EMBO Journal, 2006, v. 25, n. 3, p. 565, doi. 10.1038/sj.emboj.7600952
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- Article
A highly selective telomerase inhibitor limiting human cancer cell proliferation.
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- EMBO Journal, 2001, v. 20, n. 24, p. 6958, doi. 10.1093/emboj/20.24.6958
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- Article
A highly selective telomerase inhibitor limiting human cancer cell proliferation.
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- EMBO Journal, 2001, v. 20, n. 24, p. 6958, doi. 10.1093/emboj/20.24.6958
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- Article
Human telomerase contains two cooperating telomerase RNA molecules.
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- EMBO Journal, 2001, v. 20, n. 13, p. 3526, doi. 10.1093/emboj/20.13.3526
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- Article
A Role for Human DNA Polymerase λ in Alternative Lengthening of Telomeres.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2365, doi. 10.3390/ijms22052365
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- Article
Subtelomeric repetitive elements determine TERRA regulation by Rap1/Rif and Rap1/Sir complexes in yeast.
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- EMBO Reports, 2011, v. 12, n. 6, p. 587, doi. 10.1038/embor.2011.73
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- Article
Tel1 kinase and subtelomere-bound Tbf1 mediate preferential elongation of short telomeres by telomerase in yeast.
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- EMBO Reports, 2007, v. 8, n. 11, p. 1080, doi. 10.1038/sj.embor.7401082
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- Article
Telomerase limits the extent of base pairing between template RNA and telomeric DNA.
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- EMBO Reports, 2005, v. 6, n. 4, p. 361, doi. 10.1038/sj.embor.7400374
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- Article
Intracellular trafficking of yeast telomerase components.
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- 2002
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- Publication type:
- Report
Telomere Length Homeostasis Responds to Changes in Intracellular dNTP Pools.
- Published in:
- Genetics, 2013, v. 193, n. 4, p. 1095, doi. 10.1534/genetics.112.149120
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- Article
Telomerase Is Essential to Alleviate Pif1-Induced Replication Stress at Telomeres.
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- Genetics, 2009, v. 183, n. 3, p. 779, doi. 10.1534/genetics.109.107631
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- Article
A three-state model for the regulation of telomerase by TERRA and hnRNPA1.
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- Nucleic Acids Research, 2013, v. 41, n. 19, p. 9117, doi. 10.1093/nar/gkt695
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- Article
The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase.
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- Nucleic Acids Research, 2010, v. 38, n. 17, p. 5797, doi. 10.1093/nar/gkq296
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- Article
Saccharomyces cerevisiae Ebs1p is a putative ortholog of human Smg7 and promotes nonsense-mediated mRNA decay.
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- Nucleic Acids Research, 2007, v. 35, n. 22, p. 7688, doi. 10.1093/nar/gkm912
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- Article
Protein–RNA and protein–protein interactions mediate association of human EST1A/SMG6 with telomerase.
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- Nucleic Acids Research, 2007, v. 35, n. 20, p. 7011, doi. 10.1093/nar/gkm724
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- Article
Human shelterin protein POT1 prevents severe telomere instability induced by homology‐directed DNA repair.
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- EMBO Journal, 2020, v. 39, n. 23, p. 1, doi. 10.15252/embj.2020104500
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- Article
SMCHD1 promotes ATM‐dependent DNA damage signaling and repair of uncapped telomeres.
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- EMBO Journal, 2020, v. 39, n. 7, p. 1, doi. 10.15252/embj.2019102668
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- Article
Low- to high-throughput analysis of telomerase modulators with Telospot.
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- Nature Methods, 2007, v. 4, n. 10, p. 851, doi. 10.1038/nmeth1099
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- Article
Structure of active dimeric human telomerase.
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- Nature Structural & Molecular Biology, 2013, v. 20, n. 4, p. 454, doi. 10.1038/nsmb.2530
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- Article
The finger subdomain of yeast telomerase cooperates with Pif1p to limit telomere elongation.
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- Nature Structural & Molecular Biology, 2006, v. 13, n. 8, p. 734, doi. 10.1038/nsmb1126
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- Article
Regulation of the human telomerase reverse transcriptase gene.
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- Oncogene, 2002, v. 21, n. 4, p. 541, doi. 10.1038/sj.onc.1205081
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- Article
Rearrangements of minisatellites in the human telomerase reverse transcriptase gene are not correlated with its expression in colon carcinomas.
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- Oncogene, 2001, v. 20, n. 20, p. 2600, doi. 10.1038/sj.onc.1204346
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- Article
CSL controls telomere maintenance and genome stability in human dermal fibroblasts.
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- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11785-7
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- Article
The THO complex component Thp2 counteracts telomeric R-loops and telomere shortening.
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- EMBO Journal, 2013, v. 32, n. 21, p. 2861, doi. 10.1038/emboj.2013.217
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- Article
TERRA: telomeric repeat-containing RNA.
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- EMBO Journal, 2009, v. 28, n. 17, p. 2503, doi. 10.1038/emboj.2009.166
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- Article
Molecular biology: Damage control.
- Published in:
- Nature, 2007, v. 448, n. 7157, p. 1001, doi. 10.1038/4481001a
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- Article
The PIAS homologue Siz2 regulates perinuclear telomere position and telomerase activity in budding yeast.
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- Nature Cell Biology, 2011, v. 13, n. 7, p. 867, doi. 10.1038/ncb2263
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- Article
Yeast telomerase is specialized for C/A‐rich RNA templates.
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- Nucleic Acids Research, 2003, v. 31, n. 6, p. 1646, doi. 10.1093/nar/gkg261
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- Article
Detection of promoter activity by flow cytometric analysis of GFP reporter expression.
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- Nucleic Acids Research, 2002, v. 30, n. 14, p. e65, doi. 10.1093/nar/gnf064
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- Article
Telomerase-dependent repeat divergence at the 3′ ends of yeast telomeres.
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- Nucleic Acids Research, 2000, v. 28, n. 14, p. 2690, doi. 10.1093/nar/28.14.2690
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- Article
Method for determining RNA 34 ends and application to human telomerase RNA.
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- Nucleic Acids Research, 1996, v. 24, n. 3, p. 532, doi. 10.1093/nar/24.3.532
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- Article
Functional characterization of the TERRA transcriptome at damaged telomeres.
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- Nature Communications, 2014, v. 5, n. 10, p. 1, doi. 10.1038/ncomms6379
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- Article
A quantitative telomeric chromatin isolation protocol identifies different telomeric states.
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- Nature Communications, 2013, v. 4, n. 11, p. 2848, doi. 10.1038/ncomms3848
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- Article
The human CST complex is a terminator of telomerase activity.
- Published in:
- Nature, 2012, v. 488, n. 7412, p. 540, doi. 10.1038/nature11269
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- Article
The THO complex counteracts TERRA R-loop-mediated telomere fragility in telomerase<sup>+</sup> cells and telomeric recombination in ALT<sup>+</sup> cells.
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- Nucleic Acids Research, 2023, v. 51, n. 13, p. 6702, doi. 10.1093/nar/gkad448
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- Article
human telomeric proteome during telomere replication.
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- Nucleic Acids Research, 2021, v. 49, n. 21, p. 12119, doi. 10.1093/nar/gkab1015
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- Article
TERRA biogenesis, turnover and implications for function
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- FEBS Letters, 2010, v. 584, n. 17, p. 3812, doi. 10.1016/j.febslet.2010.07.032
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- Article
TERRA Promotes Telomere Shortening through Exonuclease 1--Mediated Resection of Chromosome Ends.
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- PLoS Genetics, 2012, v. 8, n. 6, p. 1, doi. 10.1371/journal.pgen.1002747
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- Article
Challenging endings: How telomeres prevent fragility.
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- BioEssays, 2021, v. 43, n. 10, p. 1, doi. 10.1002/bies.202100157
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- Article
Direct activation of TERT transcription by c-MYC.
- Published in:
- Nature Genetics, 1999, v. 21, n. 2, p. 220, doi. 10.1038/6010
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- Article
Telomerase Inhibitors from Cyanobacteria: Isolation and Synthesis of Sulfoquinovosyl Diacylglycerols from Microcystis aeruguinosa PCC 7806.
- Published in:
- Chemistry - A European Journal, 2013, v. 19, n. 14, p. 4596, doi. 10.1002/chem.201203296
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- Article