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- Title
Torsades de Pointes Ventricular Tachycardia Induced by Mosapride and Flecainide in the Presence of Hypokalemia.
- Authors
Ohki, Ruri; Takahashi, Masafumi; Mizuno, Osamu; Fujikawa, Hideyuki; Mitsuhashi, Takeshi; Katsuki, Takaaki; Ikeda, Uichi; Shimada, Kazuyuki
- Abstract
We report a 68-year-old man who developed torsades de pointes ventricular tachycardia induced by combined use of mosapride and flecainide. He had a permanent pacemaker (DDD mode] implanted because of sick sinus syndrome (bradytachy syndrome) 6 years earlier. The patient had started taking mosapride for upper abdominal discomfort 2 weeks earlier. On admission, ECG showed prolongation of the QTc interval from 0.48 to 0.56 seconds and self-terminating torsades de pointes occurred. We considered that this proarrhythmia was induced by mosapride in combination with antiarrhythmic agents.
- Subjects
VENTRICULAR tachycardia; TACHYCARDIA; ARRHYTHMIA; FLECAINIDE; HYPOKALEMIA; MYOCARDIAL depressants; CARDIOLOGY
- Publication
Pacing & Clinical Electrophysiology, 2001, Vol 24, Issue 1, p119
- ISSN
0147-8389
- Publication type
Article
- DOI
10.1046/j.1460-9592.2001.00119.x