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- Title
Interaction between filaggrin mutations and neonatal cat exposure in atopic dermatitis.
- Authors
Thyssen, Jacob P.; Ahluwalia, Tarunveer S.; Paternoster, Lavinia; Ballardini, Natalia; Bergström, Anna; Melén, Erik; Chawes, Bo L.; Stokholm, Jakob; Hourihane, Jonathan O'B; O'Sullivan, Donnchadh M.; Bager, Peter; Melbye, Mads; Bustamante, Mariona; Torrent, Maties; Esplugues, Ana; Duijts, Liesbeth; Hu, Chen; Elbert, Niels J.; Pasmans, Suzanne G. M. A.; Nijsten, Tamar E. C.
- Abstract
To the Editor, Atopic dermatitis (AD) is a prevalent inflammatory skin disease. The I FLG- i stratified analyses showed a trend toward cat exposure being a risk factor in children with I FLG i mutations and a protective factor in children without I FLG i mutations (Figure and Table S3). GLO:1X5/01jun20:all14162-fig-0001.jpg PHOTO (COLOR): Interaction between cat exposure and common FLG mutations in relation to (A) early-onset atopic dermatitis, (B) current atopic dermatitis, and (C) atopic dermatitis in the first 7 y of life gl We found no interaction between cat exposure in infancy and mutations in I FLG i on "early-onset AD" or "AD ever.".
- Subjects
ATOPIC dermatitis; CATS; ALLERGIC rhinitis; MULTIPLE birth; GENOTYPE-environment interaction
- Publication
Allergy, 2020, Vol 75, Issue 6, p1481
- ISSN
0105-4538
- Publication type
Article
- DOI
10.1111/all.14162