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- Title
Synthesis of aminopyrrolo[1,2-a]thieno[3,2-e]pyrazine derivatives as serotoninergic 5-HT<sub>7</sub> ligands.
- Authors
Pavé, Grégoire; Lazar, Saïd; Lesnard, Aurélien; Rault, Sylvain; Guillaumet, Gérald
- Abstract
A series of piperazinopyrrolo[1,2-a]thieno[3,2-e]pyrazine derivatives were prepared and evaluated to determine their affinity for the 5-HT7 receptor. Various substitutions on piperazine were explored as well as replacement of the piperazine by other amines.
- Subjects
SEROTONIN; LIGANDS (Chemistry); PIPERAZINE; AZACONAZOLE; CINNARIZINE; AMINES; HIPPOCAMPUS (Brain); THALAMUS; CEREBRAL cortex
- Publication
ARKIVOC: Online Journal of Organic Chemistry, 2010, p116
- ISSN
1551-7004
- Publication type
Article