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- Title
Potassium channels (including KCNQ) and epilepsy.
- Authors
Cooper, Edward C.
- Abstract
Potassium channels are integral to neuronal excitability. They set the resting membrane potential and shape depolarizations caused by excitatory synaptic inputs and action potentials. One potassium channel subgroup-alternatively called the KCNQ, Kv7, or M-channels-has recently emerged as a viable target for antiepileptic drugs. For an expanded treatment of this topic see Jasper's Basic Mechanisms of the Epilepsies, Fourth Edition (Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, eds) published by Oxford University Press (available on the National Library of Medicine Bookshelf [NCBI] at ).
- Subjects
POTASSIUM channels; EPILEPSY; BRAIN diseases; DEVELOPMENTAL disabilities; SEIZURES (Medicine)
- Publication
Epilepsia (Series 4), 2010, Vol 51, p10
- ISSN
0013-9580
- Publication type
Article
- DOI
10.1111/j.1528-1167.2010.02796.x