We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Neurological Manifestations and Comorbidities in Coronavirus Disease 2019 (COVID-19) Patients: Multicenter Study.
- Authors
Bülbül, Nazlı Gamze; Atmaca, Murat Mert; Karşıdağ, Sibel; Ateş, Miruna Florentina; Selbest, Burcu; Eren, Fettah; Güler, Sibel; Şimşek, Uğur Burak; Yetkin, Mehmet Fatih; Akçakoyunlu, Merve; Biçer, Elif Özge; Kılıç, Soner; Taş, Şazimet; Kocakaya, Zeynep; Karasu, Kevser; Yüksel, Ufuk; Kılıç, Ayşegül Ulu; Türe, Zeynep; Tutar, Nuri; Ketencioğlu, Burcu Baran
- Abstract
Objective: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, responsible for the Coronavirus Disease 2019 (COVID-19) pandemic, originated in China and swiftly spread globally, resulting in significant mortality worldwide. We aimed to create an overview of the significant symptoms, clinical indicators, and concurrent comorbidities observed in COVID-19 patients that require hospitalization and neurology consultation, adversely affecting the severe course of the disease and leading to mortality. Materials and Methods: We designed our study as a multicenter and cross-sectional survey, which was conducted with patients hospitalized in seven medical centers in Türkiye over six months. Results: A cohort of 504 patients diagnosed with COVID-19 were included in the study. In terms of the complaints at the time of admission, high fever (48%), cough (45%), sore throat (23%), and diarrhea (9%) were the most common symptoms expressed by the patients. The most commonly observed symptoms included myalgia (55%), headache (46%), loss of taste (46%), and loss of smell (39%). Furthermore, 68 patients (13.5%) within the cohort had a history of neurological diseases, distributed as follows: cerebrovascular attack (4%), migraine (2.8%), extrapyramidal disease (1.8%), dementia (1%), polyneuropathy (1%), epilepsy (0.6%), and demyelinating disease (0.6%). In the logistic regression analysis, key factors affecting mortality were identified as body mass index and age. Conclusion: The most common complaints in COVID-19 patients were high fever and sore throat. Fatigue, myalgia, headache, loss of smell, and taste were the most common symptoms. Accompanying comorbid diseases increased the severity of COVID-19 disease. Advanced age and body mass index were effective factors on mortality.
- Subjects
TURKEY; CHINA; SARS-CoV-2; COVID-19; TASTE disorders; CORONAVIRUS diseases; NEUROLOGIC manifestations of general diseases; COVID-19 pandemic; NEUROLOGICAL disorders
- Publication
Journal of Clinical Practice & Research, 2024, Vol 46, Issue 4, p391
- ISSN
2980-2156
- Publication type
Article
- DOI
10.14744/cpr.2024.94593