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- Title
Hemophagocytosis and miliary tuberculosis in a patient in the intensive care unit.
- Authors
Khan, Fahmi Yousef; Fawzy, Zeinab; Siddiqui, Issar; Yassin, Mohamed A.
- Abstract
We report a 60-year-old woman who was admitted to our hospital with high-grade fever and dyspnea. Laboratory findings showed pancytopenia and examination of aspirated bone marrow showed mature histiocytes with marked hemophagocytosis. The patient's condition continued to deteriorate despite adequate antibiotic coverage. Her respiratory condition worsened, so she was transferred to the ICU and ventilated. Transbroncheal biopsy was performed, which showed caseating granuloma suggesting pulmonary TB. Eight weeks later, bone marrow culture in Lowenstein media confirmed the presence of mycobacterium tuberculosis susceptible to INH, Rifampcine, pyrasinamide, ethambutol and streptomycin. Though antituberculous therapy was started, she died after 28 days of hospitalization.
- Subjects
DISEASES in older people; DYSPNEA; BONE marrow diseases; TUBERCULOSIS; STREPTOMYCIN; MACROPHAGES
- Publication
Indian Journal of Critical Care Medicine, 2006, Vol 10, Issue 2, p112
- ISSN
0972-5229
- Publication type
Article
- DOI
10.4103/0972-5229.25924