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- Title
Exchange transfusion for severe malaria: A comparison of red exchange with whole blood exchange.
- Authors
Udani, S.; Deshpande, A.; Kalgutkar, S.
- Abstract
To compare exchange transfusions done for severe malaria using the traditional whole blood exchange method with therapeutic red cell exchange (TREX) done using a Cobe spectra cell separator. The TREX took less time per 100 ml of blood exchanged, resulted in a 24% more efficient decrease in the IR and required less donor plasma. 3/3 tolerated the TREX well whereas one child had complications of hypocalcemia and acidosis with the whole blood exchange. The rise in hemoglobin/hematocrit was comparable in both and the platelet count was not significantly altered in either group. There was no significant alteration in the DIC profile in either group. All 6 children recovered within comparable time frames. The TREX was safer, more efficacious and less time consuming. This procedure is recommended whenever available for red cell exchange in malaria.
- Subjects
MALARIA; BLOOD transfusion; ERYTHROCYTES; HEMATOCRIT; HYPOCALCEMIA
- Publication
Indian Journal of Critical Care Medicine, 2003, Vol 7, Issue 2, p124
- ISSN
0972-5229
- Publication type
Article