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- Title
The Role of Monoacylglycerol Lipase (MAGL) in the Cancer Progress.
- Authors
Qin, Hong; Ruan, Zhi-hua
- Abstract
In recent years, metabolism is talked highly important in cancer research, especially the lipid metabolism. Researchers believe that the de novo fatty acid synthesis plays an important role in tumor development, while many studies illustrated that Endocannabinoids have anti-tumorigenic actions, including anti-proliferation, apoptosis induction, and anti-metastatic effects, MAGL as an important decomposing enzyme of both lipid metabolism and endocannabinoids system, additionally as a part of a gene expression signature contributes to different aspects of tumourigenesis.
- Subjects
FATTY acid synthesis; LIPID metabolism; CANCER research; CANNABINOIDS; ANTINEOPLASTIC agents; GENE expression; TUMOR growth; APOPTOSIS
- Publication
Cell Biochemistry & Biophysics, 2014, Vol 70, Issue 1, p33
- ISSN
1085-9195
- Publication type
Article
- DOI
10.1007/s12013-014-9899-2