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- Title
Diagnostic accuracy of dual-source CT coronary angiography with prospective ECG-triggering on different heart rate patients.
- Authors
Sun ML; Lu B; Wu RZ; Johnson L; Han L; Liu G; Yu FF; Hou ZH; Gao Y; Wang HY; Jiang S; Yang YJ; Qiao SB; Sun, Ming-Li; Lu, Bin; Wu, Run-Ze; Johnson, Laura; Han, Lei; Liu, Gang; Yu, Fang-Fang
- Abstract
<bold>Objective: </bold>To evaluate the diagnostic accuracy of dual-source CT (DSCT) prospective ECG-triggering coronary angiography in patients with different heart rate (HR).<bold>Methods: </bold>103 patients with suspected coronary artery disease underwent DSCT prospective ECG-triggered coronary angiography and invasive coronary angiography (ICA). The patients were grouped by HR during CT scans: low HR (≤60 bpm, n = 34); medium HR (60 < HR ≤ 70 bpm, n = 36) and high HR (>70 bpm, n = 33). The sensitivity and specificity of DSCT in detecting ≥50% stenosis were compared among subgroups where ICA was the gold standard. Image quality was scored using a 4-point scale.<bold>Results: </bold>A total of 1,580 (95.9%) coronary artery segments were evaluable. Sensitivity and specificity were 82.8% and 98.4%, 88.3% and 98.7%, and 80.3% and 98.6% for different subgroups (all p > 0.05). The overall area under the curve of the receiver-operating characteristic analysis was 0.94. The image quality scores were 3.1 ± 0.3, 3.1 ± 0.3 and 3.0 ± 0.4 for subgroups (p > 0.05). The overall average effective radiation dose was 3.60 ± 1.60 mSv.<bold>Conclusion: </bold>DSCT coronary angiography with prospective ECG-triggering could be just as accurate in patients with medium to high HR compared to those with low HR.
- Subjects
CHI-squared test; COMPUTED tomography; CORONARY disease; DIAGNOSTIC imaging; HEART beat; COMPUTERS in medicine; PHARMACOKINETICS; RADIATION doses; CONTRAST media; RECEIVER operating characteristic curves; CARDIAC-gated imaging; CORONARY angiography
- Publication
European Radiology, 2011, Vol 21, Issue 8, p1635
- ISSN
0938-7994
- Publication type
journal article
- DOI
10.1007/s00330-011-2107-5