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- Title
In vitro Interaction between Ofloxacin and Cefotaxime against Gram-Positive and Gram-Negative Bacteria Involved in Serious Infections.
- Authors
Gimeno, C.; Borja, J.; Navarro, D.; Valdés, L.; García-Barbal, J.; García-de-Lomas, J.
- Abstract
The checkerboard method was used to determine the antimicrobial activity of the combination cefotaxime/ofloxacin against 217 bacterial isolates involved in serious infections. Synergy or partial synergy was observed against 19 of 34 (55.8%) Staphylococcus aureus methicillin-susceptible isolates, 4 of 47 (8.4%) Streptococcus pneumoniae isolates, 28 of 34 (82.2%) Escherichia coli isolates and 70 of 102 (68.5%) Pseudomonas aeruginosa isolates. Antagonism was not observed with any of the isolates examined.
- Publication
Chemotherapy (0009-3157), 1998, Vol 44, Issue 2, p94
- ISSN
0009-3157
- Publication type
Article
- DOI
10.1159/000007098