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- Title
CLINICAL AND MORPHOLOGICAL CORRELATIONS IN FACIAL ERYTHROSIS FROM ROSACEA: PRELIMINARY RESULTS FROM A TWO-STEP OBSERVATIONAL STUDY.
- Authors
Damaschin, Alina-Valentina; Ghiurea, Ioana-Emilia; Son, Răzvan Cătălin; Stan, Laurentiu-Raul; Vrajitoru, Rares; Tiucă, Oana Mirela; Morariu, Silviu Horia
- Abstract
Background: Rosacea is a chronic centrofacial dermatosis, mainly affecting light-skinned patients, and characterized by persistent erythema alongside, depending on the clinical stage, telangiectasias, papules, and pustules. The evaluation of cutaneous parameters and the use of newer techniques such as skin ultrasound examination, though still not so widely employed, prove to be reliable for the management and follow-up of patients suffering from this condition. Objective: Our research aimed to analyze the clinical, biological, and morphofunctional aspects of facial erythrosis in patients suffering from rosacea and to highlight a possible link between them. Material and methods: We conducted a two-step observational study that included patients diagnosed with rosacea and admitted to the Dermatology Clinic of Mures Clinical County Hospital. Data referring to sociodemographic status, disease course, subtype, trigger factors, Helicobacter Pylori association, and treatment were extracted from patients' charts and statistically analyzed using Excel software. Ultrasound examination was performed for included patients to assess the following cutaneous parameters: erythema, melanin, hydration level, and skin elasticity. Continuous variables were analyzed with Student's t-test or Mann-Whitney U test, depending on their normality check. Categorical variables were assessed for intergroup significant differences with the Exact Chisquare test using the Monte Carlo method. The present data refer to patients examined in the winter season and set to return for a second analysis during spring. Results : 20 patients were enrolled in this study. 11 were females and 9 were males. 8 were from urban areas, and 12 were from rural ones. Patients' ages ranged from 28 to 65 years old. All 3 patients with erythematotelangiectatic subtype had bilateral facial lesions, emotional stress being the trigger at 2 of them and none had Helicobacter Pylori. The majority of patients (n=12) suffering from papulopustular subtype had bilateral facial and nose lesions and a median erythema value of 12. The 4 patients with the phymatous subtype had lesions affecting the whole facial area and most of them were males (n=3). The male patient with ocular subtype (n=1) has facial and ocular involvement, more than 10 years from the beginning of the disease and an 18,9 level of erythema. A correlation between the level of hydration and rosacea (p=0,049) was found. Conclusions: As rosacea progresses, skin ultrasound parameters modify underlying the subsequent pathophysiological mechanism. Further larger prospective studies are necessary.
- Subjects
ROMANIA; SKIN inflammation; ROSACEA; SYMPTOMS; CONFERENCES &; conventions; SKIN; FACE diseases; DISEASE complications
- Publication
Acta Marisiensis. Seria Medica, 2024, Vol 70, p21
- ISSN
2668-7755
- Publication type
Article