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- Title
Akut alt solunum yolu enfeksiyonu nedeniyle hastaneye yatan çocuklarda Multiplex-PCR ile saptanan enfeksiyöz etkenlerin değerlendirilmesi.
- Authors
İrem Kanberoğlu, Gül; Güdeloğlu, Elif; Bağ, Özlem; Ömür Ecevit, Çiğdem
- Abstract
Purpose: Lower respiratory tract infections (LRTI) are significantly responsible for morbidity and mortality in children. Multiplex-PCR (M-PCR) is one of the new tests used to detect the microorganism located in the respiratory epithelium. The aim of this study is to evaluate the microbiologic agents determined by M-PCR in the diagnosis of acute LRTI and and explaining the relationship of these factors with clinical, radiological and laboratory findings. Material and methods: The medical records of pediatric patients hospitalized for acute LRTI in İzmir Dr. Behçet Uz Children’s Hospital between April 2015 and April 2017 were evaluated retrospectively. The relationship between clinical and laboratory markers on the type of pathogen and the distribution by season and month were investigated. Results: The number of the patients in the study group was 152 (M/F: 83/69; mean age: 4.91±3.76 years). In the study group, samples of 103 (67.8%) cases were found to be M-PCR positive. The age range in which M-PCR is most frequently found positive was 3 months-5 years. The most common factor in M-PCR (+) cases was viral factors (62.13%) and the most common virus was Rhinovirus (32%), 2nd frequent was Respiratory syncytial virus (RSV) infections (22.3%). On the other hand, bacteria were detected in 37.9% of the patients, while Streptococcus pneumoniae (S.pneumoniae) was the most common bacteria (22.3%), 2nd frequency was Stafilococcus aureus (S.aureus) (11.6%). Conclusion: M-PCR was found to be highly positive (67%) in documenting a factor in LRTI. Thus, M-PCR may play an important role in reducing the use of unnecessary antibiotics and detailed laboratory tests fort he patient's with LRTI most of which are caused by viral pathogens.
- Publication
Pamukkale Medical Journal, 2021, Vol 14, Issue 3, p604
- ISSN
1309-9833
- Publication type
Article
- DOI
10.31362/patd.812420