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- Title
Cytokines: IRF7 lost in translation.
- Authors
Papatriantafyllou, Maria
- Abstract
The article focuses on a research related to pro-inflammatory expression of cytokines that must be regulated to avoid inflammatory disorders. . It reflects that mice 2'-5'-oligoadenylate synthase like protein 1 (OASL1) mediates a transcriptional control for the regulation of interferon-regulatory factor 7 (IRF7) and the downstream response of type I interferons. It presents the future expectation related to human homologue of OASL1 in humans to increase antiviral responses.
- Subjects
IMMUNOLOGY of inflammation; THERAPEUTIC use of cytokines; GENETIC translation; GENETIC transcription; ANTIVIRAL agents
- Publication
Nature Reviews Immunology, 2013, Vol 13, Issue 4, p221
- ISSN
1474-1733
- Publication type
journal article
- DOI
10.1038/nri3425