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- Title
Acute post-exercise change in blood pressure and exercise training response in patients with coronary artery disease.
- Authors
Kiviniemi, Antti M.; Hautala, Arto J.; Karjalainen, Jaana J.; Piira, Olli-Pekka; Lepojärvi, Samuli; Ukkola, Olavi; Huikuri, Heikki V.; Tulppo, Mikko P.
- Abstract
We tested the hypothesis that acute post-exercise change in blood pressure (BP) may predict exercise training responses in BP in patients with coronary artery disease (CAD). Patients with CAD (n = 116, age 62 ± 5 years, 85men) underwent BP assessments at rest and during 10-min recovery following a symptom-limited exercise test before and after the 6-month training intervention (one strength and 3-4 aerobic moderate-intensity exercises weekly). Post-exercise change in systolic BP (SBP) was calculated by subtracting resting SBP from lowest post-exercise SBP. The training-induced change in resting SBP was -2 ± 13mmHg (p = 0.064), ranging from -42 to 35mmHg. Larger post-exercise decrease in SBP and baseline resting SBP predicted a larger training-induced decrement in SBP (β = 0.46 and β = -0.44, respectively, p < 0.001 for both). Acute post-exercise decrease in SBP provided additive value to baseline resting SBP in the prediction of training-induced change in resting SBP (R2 from 0.20 to 0.26, p = 0.002). After further adjustments for other potential confounders (sex, age, baseline body mass index, realized training load), post-exercise decrease in SBP still predicted the training response in resting SBP (β = 0.26, p = 0.015). Acute post-exercise change in SBP was associated with training-induced change in resting SBP in patients with CAD, providing significant predictive information beyond baseline resting SBP.
- Subjects
COOLDOWN; BLOOD pressure; CORONARY disease; EXERCISE physiology; HYPERTENSION; PATIENTS
- Publication
Frontiers in Physiology, 2015, Vol 5, p1
- ISSN
1664-042X
- Publication type
Article
- DOI
10.3389/fphys.2014.00526