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- Title
Association of Existence of Sarcopenia and Poor Recovery of Swallowing Function in Post-Stroke Patients with Severe Deglutition Disorder: A Multicenter Cohort Study.
- Authors
Nishioka, Shinta; Fujishima, Ichiro; Kishima, Masako; Ohno, Tomohisa; Shimizu, Akio; Shigematsu, Takashi; Itoda, Masataka; Wakabayashi, Hidetaka; Kunieda, Kenjiro; Oshima, Fumiko; Ogawa, Sumito; Fukuma, Kazuki; Ogawa, Nami; Kayashita, Jun; Yamada, Minoru; Mori, Takashi; Onizuka, Shinya
- Abstract
Background: The effect of sarcopenia on the recovery of swallowing function, and the interaction among sarcopenia, nutrition care, and rehabilitation therapy are inconclusive. Methods: This multicenter cohort study was conducted between November 2018 and October 2020 in convalescent rehabilitation hospitals in Japan and included post-stroke patients aged ≥65 years with dysphagia. All participants were assigned to sarcopenia and non-sarcopenia groups. The primary outcome was the achievement of ≥2 Food Intake Level Scale [FILS] gain, and the secondary outcomes included Functional Independence Measure (FIM) gain and efficiency. Considering the effect modification of energy intake and rehabilitation duration, logistic regression analyses were performed. Results: Overall, 153 participants with (median age, 82 years; 57.5% women) and 40 without (median age 75 years; 35.0% women) sarcopenia were included. The non-sarcopenia group had more patients who achieved an FILS gain of ≥2 (75.0%) than the sarcopenia group (51.0%). Sarcopenia was independently associated with a poor FILS gain (odds ratio:0.34, 95% confidence intervals: 0.13–0.86) but not associated with FIM gain or efficiency. This association was not affected by the rehabilitation duration or energy intake. Conclusions: In conclusion, sarcopenia was negatively associated with the recovery of swallowing function in stroke patients without interaction by energy intake and rehabilitation duration.
- Subjects
JAPAN; THERAPEUTICS; RESEARCH; DEGLUTITION; CONFIDENCE intervals; CONVALESCENCE; FUNCTIONAL status; SARCOPENIA; DEGLUTITION disorders; TREATMENT effectiveness; STROKE patients; DESCRIPTIVE statistics; MUSCLE strength; LOGISTIC regression analysis; ODDS ratio; LONGITUDINAL method; EVALUATION
- Publication
Nutrients, 2022, Vol 14, Issue 19, p4115
- ISSN
2072-6643
- Publication type
Article
- DOI
10.3390/nu14194115