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- Title
Hypertension and other risk factors for the development of kidney cancer (renal cell carcinoma) in a Japanese population: findings from the JACCC study.
- Authors
Washio M; Mori M; Sakauchi F; Watanabe Y; Ozasa K; Hayashi K; Miki T; Nakao M; Mikami K; Ito Y; Kubo T; Wakai K; Tamakoshi A
- Abstract
Background: Although the incidence of kidney cancer in Japan is lower than the rates in the other developed countries, there is no doubt that in Japan the incidence rate of kidney cancer has increased recently. Methods: We evaluated the risk factors of kidney cancer using the database of the Japan Collaborative Cohort (JACC) study in 62,869 subjects (25,348 men and 37,521 women). Cox-proportional hazards model was used to determine age-and-sex adjusted relative risk. Results: During the follow-up of 7.6 years, we identified 40 incident cases of kidney cancer (renal cell carcinoma). Hypertension and kidney disease were revealed as significant risk factors for kidney cancer. Both systolic and diastolic blood pressure showed a positive relation to the development of kidney cancer risk. Conclusion: The present study suggests that hypertension and kidney disease may be associated with an increased risk for the development of kidney cancer.
- Publication
International Medical Journal, 2008, Vol 15, Issue 5, p343
- ISSN
1341-2051
- Publication type
Journal Article