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- Title
Green Tea (Camellia sinensis) Ameliorates Retinopathy and Renal Mitochondrial Defects but Deteriorates Collagen Glycoxidation and Cross-Linking in Experimental Diabetes.
- Authors
MUSTATA, GEORGIAN T.; ROSCA, MARIANA G.; REIHL, OLIVER; BIEMEL, KLAUS; SMITH, MARK A.; VISWANATHAN, ASHWINI; STRAUCH, CHRISTOPHER; DU, YUN PENG; KERN, TIMOTHY S.; LEDERER, MARKUS; BROWNLEE, MICHAEL; WEISS, MIRIAM F.; MONNIER, VINCENT M.
- Abstract
The article reports on a study which reveals that green tea (GT) improves retinopathy and renal mitochondrial defects, but worsens collagen glycoxidation in diabetes. It is stated that three groups of streptozotocininduced diabetic Lewis rats were treated for 12 months with tap water and fresh Japanese GT extract. It was found that GT with vitamins C and E act against oxidative processes in diabetes, but these tend to deteriorate carbonyl stress in the extracellular matrix.
- Subjects
GREEN tea; DIABETES complications; EXTRACELLULAR matrix; COLLAGEN; MEDICAL research; THERAPEUTICS
- Publication
Annals of the New York Academy of Sciences, 2005, Vol 1043, Issue 1, p940
- ISSN
0077-8923
- Publication type
Article
- DOI
10.1196/annals.1333.154