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- Title
The role of extracorporeal life support for patients with COVID-19: Preliminary results from a statewide experience.
- Authors
Sultan, Ibrahim; Habertheuer, Andreas; Usman, Asad A.; Kilic, Arman; Gnall, Eric; Friscia, Michael E.; Zubkus, Dmitriy; Hirose, Hitoshi; Sanchez, Pablo; Okusanya, Olugbenga; Szeto, Wilson Y.; Gutsche, Jacob
- Abstract
<bold>Objective: </bold>There is a paucity of clinical data on critically ill patients with COVID-19 requiring extracorporeal life support.<bold>Methods: </bold>A statewide multi-institutional collaborative for COVID-19 patients was utilized to obtain clinical data on the first 10 critically ill COVID-19 patients who required extracorporeal membrane oxygenation (ECMO).<bold>Results: </bold>Of the first 10 patients that required ECMO for COVID-19, the age ranged from 31 to 62 years with the majority (70%) being men. Seven (70%) had comorbidities. The majority (80%) of patients had known sick contact and exposure to COVID-19 positive patients or traveled to pandemic areas inside the United States within the 2 weeks before symptom onset. None of the patients were healthcare workers. The most common symptoms leading to the presentation were high fever ≥103°F (90%), cough (80%) and dyspnea (70%), followed by fatigue and gastrointestinal symptoms (both 30%), myalgia, loss of taste, pleuritic chest pain, and confusion (all 10%). All patients had bilateral infiltrates on chest X-rays suggestive of interstitial viral pneumonia. All patients were cannulated in the venovenous configuration. Two (20%) patients were successfully liberated from ECMO support after 7 and 10 days, respectively, and one (10%) patient is currently on a weaning course. One patient (10%) died after 9 days on ECMO from multiorgan dysfunction.<bold>Conclusions: </bold>These preliminary multi-institutional data from a statewide collaborative offer insight into the clinical characteristics of the first 10 patients requiring ECMO for COVID-19 and their initial clinical course. Greater morbidity and mortality is likely to be seen in these critically ill patients with longer follow-up.
- Subjects
UNITED States; EXTRACORPOREAL membrane oxygenation; COVID-19; TASTE disorders; COUGH; PULMONARY fibrosis; ADULT respiratory distress syndrome treatment; CORONAVIRUS disease treatment; VIRAL pneumonia; CAUSES of death; RESEARCH; RESEARCH methodology; RETROSPECTIVE studies; EVALUATION research; MEDICAL cooperation; CATASTROPHIC illness; HOSPITAL mortality; RISK assessment; ADULT respiratory distress syndrome; TREATMENT effectiveness; COMPARATIVE studies; EPIDEMICS; LONGITUDINAL method
- Publication
Journal of Cardiac Surgery, 2020, Vol 35, Issue 7, p1410
- ISSN
0886-0440
- Publication type
journal article
- DOI
10.1111/jocs.14583