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- Title
3-Isothiocyanato Oxindoles Serving as Powerful and Versatile Precursors to Structurally Diverse Dispirocyclic Thiopyrrolidineoxindoles through a Cascade Michael/Cyclization Process with Amino-Thiocarbamate Catalysts.
- Authors
Han, Wen‐Yong; Li, Shi‐Wu; Wu, Zhi‐Jun; Zhang, Xiao‐Mei; Yuan, Wei‐Cheng
- Abstract
Cascading catalysis: 3‐Isothiocyanato oxindoles act as powerful and versatile precursors for a range of structurally diverse dispirocyclic thiopyrrolidineoxindoles containing two spiro‐quaternary and three contiguous stereogenic centers in quantitative yields with excellent disatereo‐ and enantioselectivities by only using 1 mol % amino‐thiocarbamate catalyst.
- Publication
Chemistry - A European Journal, 2013, Vol 19, Issue 18, p5551
- ISSN
0947-6539
- Publication type
Article
- DOI
10.1002/chem.201300206