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- Title
Urosepsis: Pathophysiologie, Diagnose und Management – ein Update.
- Authors
Stangl, Fabian; Wagenlehner, Florian; Schneidewind, Laila; Kranz, Jennifer
- Abstract
Urinary tract infections vary widely in their clinical spectrum, ranging from uncomplicated cystitis to septic shock. Urosepsis accounts for 9–31% of all cases of septicemia and is often associated with nosocomial infections. A major risk factor for urosepsis is the presence of obstructive uropathy, caused by conditions such as urolithiasis, tumors, or strictures. The severity and course of urosepsis depend on both the virulence of the pathogen and the patient's specific immune response. Prompt therapy, including antimicrobial treatment and eradication of the infection source, along with supportive measures for circulatory and respiratory stabilization, and adjunctive therapies such as hemodialysis and glucocorticoid therapy, is crucial. Due to demographic changes, an increase in cases of urosepsis is expected—thus, it is of utmost importance for urologists to be familiar with targeted diagnostics and effective treatment.
- Subjects
URINARY tract infection diagnosis; URINARY tract infections; BLOOD; CROSS infection; UROLOGISTS; URETERIC obstruction; URINARY calculi; CYSTITIS; HEMODIALYSIS; ANTI-infective agents; CELL culture; SEPSIS; GLUCOCORTICOIDS
- Publication
Die Urologie, 2024, Vol 63, Issue 6, p543
- ISSN
2731-7064
- Publication type
Article
- DOI
10.1007/s00120-024-02336-0