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- Title
Limitations in Research on Maintenance Treatment for Individuals With Schizophrenia.
- Authors
Horowitz, Mark Abie; Macaulay, Alex; Taylor, David
- Abstract
2020; 1(1). doi:10.1093/schizbullopen/sgaa002 5 Liu CC, Takeuchi H. Achieving the lowest effective antipsychotic dose for patients with remitted psychosis: a proposed guided dose-reduction algorithm. Oral antipsychotics not specified, implied abrupt.b</td></tr><tr><td valign="top" align="left" scope="col">Dellva et al, 1997</td><td valign="top" align="left" /><td valign="top" align="left" /></tr><tr><td valign="top" align="left" scope="row"> Study 1 (referred to as Beasley et al, 1996a in original article)</td><td valign="top" align="left">Not specified; outpatients remitted on antipsychotics. Comment & Response B To the Editor b We appreciate the clinical value of the dose-response meta-analysis performed by Leucht and colleagues.[1] The interpretation provided was that doses above 5 mg/d risperidone equivalent do not provide additional protection against relapse, while the risk of relapse increases rapidly (and apparently hyperbolically) for doses less than 2.5 mg/d risperidone equivalent.
- Subjects
PEOPLE with schizophrenia; DRUG therapy for schizophrenia; PSYCHOLOGY; ANTIPSYCHOTIC agents
- Publication
JAMA Psychiatry, 2022, Vol 79, Issue 1, p83
- ISSN
2168-622X
- Publication type
journal article
- DOI
10.1001/jamapsychiatry.2021.3400