We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Selective Serotonin Reuptake Inhibitor Use During Pregnancy-Associated With but Not Causative of Autism in Offspring.
- Authors
Flores, José M.; Avila-Quintero, Victor J.; Bloch, Michael H.
- Abstract
If an expectant mother continues to take an antidepressant medication during pregnancy, it is typically because she and her physician have made a conscious decision to continue the medication during pregnancy - presumably because the condition is sufficiently severe and/or the risk of relapse is substantial. Therefore, mothers who continue SSRIs during pregnancy may have a more severe mental illness, and it may be the illness, not the medication exposure, that is associated with the increased risk of ASD in offspring. The lack of a likely true causal association between maternal SSRI exposure in pregnancy and ASD in the offspring is further highlighted by the observation that antidepressant use before (not only during) pregnancy is also associated with an increased risk of ASD.[1] Thus, recent antidepressant use (in the absence of possible teratogenic exposure to the fetus) is also associated with increased risk of ASD in offspring.[[3]].
- Subjects
SEROTONIN uptake inhibitors; TEENAGE suicide; PREGNANCY; DRUG side effects; AUTISM
- Publication
JAMA Psychiatry, 2019, Vol 76, Issue 12, p1225
- ISSN
2168-622X
- Publication type
editorial
- DOI
10.1001/jamapsychiatry.2019.2193