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- Title
Melasma: Updates and perspectives.
- Authors
Kwon, Soon‐Hyo; Na, Jung‐Im; Choi, Ji‐Young; Park, Kyoung‐Chan
- Abstract
Management of melasma is highly challenging due to inconsistent treatment results and frequent relapses. However, recent studies revealed that melasma may not only be a disease of melanocytes, but also a photoaging skin disorder. Herein, we attempt to validate that melasma is indeed a photoaging disorder by presenting the histopathologic findings of melasma: solar elastosis, altered basement membrane, increased vascularization and increased mast cell count. We also provide some therapeutic implications based on these findings and a discussion on the latest updates and perspectives regarding treatment.
- Subjects
MELANOSIS; BASAL lamina; MAST cells; THERAPEUTICS
- Publication
Experimental Dermatology, 2019, Vol 28, Issue 6, p704
- ISSN
0906-6705
- Publication type
Article
- DOI
10.1111/exd.13844