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- Title
Permanent draft genome sequence of the probiotic strain Propionibacterium freudenreichii CIRM-BIA 129 (ITG P20).
- Authors
Falentin, Hélène; Deutsch, Stéphanie-Marie; Loux, Valentin; Hammani, Amal; Buratti, Julien; Parayre, Sandrine; Chuat, Victoria; Barbe, Valérie; Aury, Jean-Marc; Jan, Gwenaël; Le Loir, Yves
- Abstract
Propionibacterium freudenreichii belongs to the class Actinobacteria (Gram positive with a high GC content). This 'Generally Recognized As Safe' (GRAS) species is traditionally used as (i) a starter for Swiss-type cheeses where it is responsible for holes and aroma production, (ii) a vitamin B12 and propionic acid producer in white biotechnologies, and (iii) a probiotic for use in humans and animals because of its bifidogenic and anti-inflammatory properties. Until now, only strain CIRM-BIA1T had been sequenced, annotated and become publicly available. Strain CIRM-BIA129 (commercially available as ITG P20) has considerable anti-inflammatory potential. Its gene content was compared to that of CIRM-BIA1 T. This strain contains 2384 genes including 1 ribosomal operon, 45 tRNA and 30 pseudogenes.
- Subjects
NUCLEOTIDE sequencing; PROBIOTICS; PROPIONIBACTERIUM; IMMUNOREGULATION; ANTI-inflammatory agents
- Publication
Standards in Genomic Sciences, 2016, Vol 11, Issue 1, p1
- ISSN
1944-3277
- Publication type
Article
- DOI
10.1186/s40793-015-0120-z