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- Title
Regulatory mechanism in sleep-wake cycle: from a receptor view.
- Authors
ZHANG Zhao-huan; LIU Zhen-yu; ZHANG Han-wen; ZHAO Zhong-xin
- Abstract
Circadian rhythm is a universal phenomenon driven by the day-night cycle among the living beings on the earth. It is considered a basic element of life, which involves oscillations of most physiological activity through the body. The coordination of the different physiologic activities should be attributed to the convergence of a diversity of regulatory mechanisms. Among the multiple links in sleep-wake cycle, the receptors are of primary importance. Since they initiate the downstream signaling leading to cell responses, the receptors are considered a commonly intervention target. Here we summarize the major receptors in sleep-wake regulation, along with a brief introduction of their functional findings, aiming to provide clues to further function understanding and intervention developing.
- Subjects
BODY composition; CELL receptors; CIRCADIAN rhythms; HORMONES; MELATONIN; NEUROSURGERY; NEUROLOGY; NEUROPEPTIDES; NEUROTRANSMITTERS; PHYSIOLOGY; SLEEP
- Publication
Chinese Journal of Contemporary Neurology & Neurosurgery, 2013, Vol 13, Issue 5, p368
- ISSN
1672-6731
- Publication type
Article
- DOI
10.3969/j.issn.1672-6731.2013.05.003