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- Title
Excess granulation tissue responses associated with isotretinoin therapy.
- Authors
Robertson, D. B.; Kubiak, E.; Gomez, E. C.
- Abstract
Multiple polypoid projections of granulation tissue developed in two patients receiving isotretinoin for acne. Histological study of the lesions revealed increased amounts of non-sulphated acid mucopolysaccharides in the ground substance of the granulation tissue stroma. Complete resolution occurred following curettage with or without chemical cautery. The role of isotretinoin in the development of these lesions is discussed.
- Subjects
ISOTRETINOIN; TRETINOIN; SURGICAL therapeutics; EXTRACELLULAR matrix; POLYSACCHARIDES; ACNE
- Publication
British Journal of Dermatology, 1984, Vol 111, Issue 6, p689
- ISSN
0007-0963
- Publication type
Article
- DOI
10.1111/j.1365-2133.1984.tb14152.x