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- Title
Combined clotting factor deficiencies: experience at a single hemophilia treatment center.
- Authors
O'BRIEN, S. H.; RITCHEY, A. K.; RAGNI, M. V.
- Abstract
We describe a series of patients with combined factor deficiencies and von Willebrand's disease (VWD) at one haemophilia treatment centre. Although the incidence of VWD is at least 1% in the general population, combined coagulation defects have been infrequently described in the medical literature and are likely under diagnosed. This entity should be considered in patients with a known factor deficiency and either an unexpectedly severe bleeding phenotype, or bleeding that is unresponsive to factor replacement.
- Subjects
VON Willebrand disease treatment; BLOOD coagulation factors; PHENOTYPES; HEMORRHAGE; BLOOD coagulation; PREVENTION
- Publication
Haemophilia, 2007, Vol 13, Issue 1, p26
- ISSN
1351-8216
- Publication type
Article
- DOI
10.1111/j.1365-2516.2006.01389.x