We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
JAK ROZPOZNAWAĆ I LECZYĆ DIVERSION COLITIS?
- Authors
Gaćkowska, Katarzyna; Pruchniak, Monika
- Abstract
Diversion colitis (DC) is a nonspecifi c infl ammation and mucosal atrophy within the large intestine segment excluded from normal bowel passage after stoma formation. The pathogenesis of DC remains unclear, but its development is likely connected with short-chain fatty acids (SCFAs) defi ciency in the intestinal lumen. The diagnosis is formulated based on clinical symptoms, endoscopic fi ndings and a histopathological examination. Surgical restoration of the gastrointestinal tract continuity is the most effective, yet not always feasible, treatment method. Alternative (pharmacological) DC treatment includes infusions of SCFAs, mesalazine enemas and local glucocorticosteroids. However, evidence for the effective conservative treatment of DC has not been suffi ciently documented. In chronic DC, an intestinal microbiota transfer procedure can be conducted experimentally. The objective of this paper is to provide a summary of the current state of knowledge on DC. The presented information and data on the pathogenesis, diagnosis and treatment of DC may contribute to a better understanding of this large intestine pathology very rarely accounted for in the Polish literature on the subject.
- Subjects
COLITIS diagnosis; THERAPEUTIC use of glucocorticoids; COLITIS treatment; GUT microbiome; ENEMA; SHORT-chain fatty acids
- Publication
Polish Nursing / Pielegniarstwo Polskie, 2022, Vol 84, Issue 2, p90
- ISSN
0860-8466
- Publication type
Article
- DOI
10.20883/pielpol.2022.9