We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Impact of routine reporting of estimated glomerular filtration rate using the European Kidney Function Consortium and Chronic Kidney Disease Epidemiology Collaboration equations in a Western Australian community population.
- Authors
Napier, Kathryn; Lim, David; Thomas, Elizabeth; Boyd, James; Chakera, Aron; Williamson, James; Betts, Kim; Manuel, Justin; Tuando, Teodulo Rey; Robinson, Suzanne
- Abstract
Aim: In 2020, the European Kidney Function Consortium (EKFC) published a new creatinine‐based equation to estimate glomerular filtration rate (eGFR) to overcome known limitations in existing equations. The aim of this study is to model the potential impact on service referral and health expenditure of routine reporting of eGFR using the EKFC equation as compared to the CKD‐EPI equation in a Western Australian population. Methods: eGFR was calculated for 760 614 patients with 2 368 234 creatinine results using the CKD‐EPI and EKFC formulas. Patients were grouped into a CKD cohort if they had at least two eGFR results of <60 ml/min/1.73 m2 from tests at least 90 days apart. The impact of each equation on the reclassification of CKD stages, CKD cohort classification, the rate of change in eGFR and direct health costs were assessed. Results: About 90.66% of patients had a lower eGFR when calculated using the EKFC equation. About 12.6% of individuals were classified into a different CKD stage using the EKFC equation with 97.43% of these patients classified into a higher (more advanced) stage. There was a 25.9% increase in the number of patients identified as having CKD when calculated using the EKFC equation. Direct health costs also increased with the use of EKFC reporting. Conclusion: Use of the EKFC equation will increase population prevalence of CKD and will result in a shift to higher stages of CKD. This has implications for monitoring and referral of patients within specialist services and has the potential to increase the need for multidisciplinary care. Summary at a glance: This study considers the application of the recently published European Kidney Function Consortium (EKFC) equation in 2020 to estimate the glomerular filtration rate. It compares the impact when shifting from the use of the CKD‐EPI equation to the EKFC equation, by modelling potential differences on service referral and health expenditure on a Western Australian community population.
- Subjects
GLOMERULAR filtration rate; CHRONIC kidney failure; KIDNEY physiology; CONSORTIA; AUSTRALIANS
- Publication
Nephrology, 2022, Vol 27, Issue 10, p823
- ISSN
1320-5358
- Publication type
Article
- DOI
10.1111/nep.14083