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- Title
Fungal Endophthalmitis Outbreak after Cataract Surgery, South Korea, 2020.
- Authors
Soo Jeong Yoon; Soo Hyun Kim; Hyun Jung Bahk; Yeong Seo Ahn; Ji Joo Lee; Hye Jin Kim; Ha Jin Lim; Min Ji Choi; Jong Hee Shin; Yeon-Kyeng Lee; Yoon, Soo Jeong; Kim, Soo Hyun; Bahk, Hyun Jung; Ahn, Yeong Seo; Lee, Ji Joo; Kim, Hye Jin; Lim, Ha Jin; Choi, Min Ji; Shin, Jong Hee; Lee, Yeon-Kyeng
- Abstract
In November 2020, an unusual increase in fungal endophthalmitis cases after cataract surgery was reported to the Korea Disease Control and Prevention Agency, South Korea. We initiated an outbreak investigation to identify the cause. We identified 156 cases nationwide, 62 confirmed and 94 probable. Most case-patients were exposed during surgery to ocular viscoelastic devices (OVDs) from the same manufacturer (company A). We isolated Fusarium spp. from 50 confirmed cases. Molecular identification of 39 fungal isolates from clinical samples and 13 isolates from OVDs confirmed F. oxysporum caused the infections. The risk ratio for fungal endophthalmitis from company A's OVDs was 86.0 (95% CI 27.4-256.9), much higher than risk from other manufacturers' products. We determined this fungal endophthalmitis outbreak was caused by a contaminated lot of OVDs and recommended discontinued use of this product. Early recognition of outbreaks and joint responses from related government agencies can reduce risk for fungal endophthalmitis.
- Publication
Emerging Infectious Diseases, 2022, Vol 28, Issue 11, p2226
- ISSN
1080-6040
- Publication type
Article
- DOI
10.3201/eid2811.220361