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- Title
SARS-CoV-2 Period Seroprevalence and Related Factors, Hillsborough County, Florida, USA, October 2020-March 2021.
- Authors
Giuliano, Anna R.; Pilon-Thomas, Shari; Schell, Michael J.; Abrahamsen, Martha; Islam, Jessica Y.; Isaacs-Soriano, Kimberly; Kennedy, Kayoko; Dukes, Christopher W.; Whiting, Junmin; Rathwell, Julie; Hensel, Jonathan A.; Mangual, Leslie N.; Schonbrunn, Ernst; Bikowitz, Melissa; Grassie, Dylan; Yang, Yan
- Abstract
Estimating the actual extent of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is challenging because virus test positivity data undercount the actual number and proportion of persons infected. SARS-CoV-2 seroprevalence is a marker of past SARS-CoV-2 infection regardless of presence or severity of symptoms and therefore is a robust biomarker of infection period prevalence. We estimated SARS-CoV-2 seroprevalence among residents of Hillsborough County, Florida, USA, to determine factors independently associated with SARS-CoV-2 antibody status overall and among asymptomatic antibody-positive persons. Among 867 participants, SARS-CoV-2 period prevalence (October 2020-March 2021) was 19.5% (asymptomatic seroprevalence was 8%). Seroprevalence was 2-fold higher than reported SARS-CoV-2 virus test positivity. Factors related to social distancing (e.g., essential worker status, not practicing social distancing, contact with a virus-positive person, and length of contact exposure time) were consistently associated with seroprevalence but did not differ by time since suspected or known infection (<6 months vs. >6 months).
- Subjects
FLORIDA; SARS-CoV-2; SEROPREVALENCE
- Publication
Emerging Infectious Diseases, 2022, Vol 28, Issue 3, p556
- ISSN
1080-6040
- Publication type
Article
- DOI
10.3201/eid2803.211495