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- Title
Drug-Resistant Tuberculosis among Children, China, 2006-2015.
- Authors
Ning-ning Tao; Yao Liu; Huai-chen Li; Xiao-chun He; Xian-xin Zhang; Chun-bao Yu; Tao, Ning-Ning; He, Xiao-Chun; Zhang, Xian-Xin; Liu, Yao; Yu, Chun-Bao; Li, Huai-Chen
- Abstract
Microbial drug resistance has become a major public health concern worldwide. To acquire epidemiologic data on drug-resistant tuberculosis (DR TB) among children, a major cause of illness and death for this population, we conducted a retrospective study of 2006-2015 data from 36 TB prevention and control institutions in Shandong Province, China. A total of 14,223 new TB cases, among which children (<18 years of age) accounted for only 5.5%, were caused by culture-confirmed Mycobacterium tuberculosis. Among children with TB, 18.9% had DR TB and 6.9% had multidrug-resistant TB. Over the past decade, the percentage of DR TB; multidrug-resistant TB; and overall first-line drug resistance for isoniazid, rifampin, ethambutol, and streptomycin among children increased significantly (at least 12%). Understanding the long-term trends of DR TB among children can shed light on the performance of TB control programs, thereby contributing to global TB control.
- Subjects
SHANDONG Sheng (China); CHINA; DRUG resistance in microorganisms; TUBERCULOSIS; CHILDREN'S health; STREPTOMYCIN; COMPARATIVE studies; LONGITUDINAL method; RETROSPECTIVE studies
- Publication
Emerging Infectious Diseases, 2017, Vol 23, Issue 11, p1800
- ISSN
1080-6040
- Publication type
journal article
- DOI
10.3201/eid2311.170234