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- Title
Postmortem Findings for 7 Neonates with Congenital Zika Virus Infection.
- Authors
Sousa, Anastácio Q.; Cavalcante, Diane I. M.; Franco, Luciano M.; Araújo, Fernanda M. C.; Sousa, Emília T.; Valença-Junior, José Telmo; Rolim, Dionne B.; Melo, Maria E. L.; Sindeaux, Pedro D. T.; Araújo, Marialva T. F.; Pearson, Richard D.; Wilson, Mary E.; Pompeu, Margarida M. L.
- Abstract
Postmortem examination of 7 neonates with congenital Zika virus infection in Brazil revealed microcephaly, ventriculomegaly, dystrophic calcifications, and severe cortical neuronal depletion in all and arthrogryposis in 6. Other findings were leptomeningeal and brain parenchymal inflammation and pulmonary hypoplasia and lymphocytic infiltration in liver and lungs. Findings confirmed virus neurotropism and multiple organ infection.
- Subjects
AUTOPSY; ZIKA virus infections; MICROCEPHALY; ARTHROGRYPOSIS; PULMONARY hypoplasia
- Publication
Emerging Infectious Diseases, 2017, Vol 23, Issue 7, p1164
- ISSN
1080-6040
- Publication type
journal article
- DOI
10.3201/eid2307.162019