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- Title
Acute Encephalopathy Associated with Influenza A Infection in Adults.
- Authors
Lee, Nelson; Chun Kwok Wong; Chan, Paul K. S.; Lindegardh, Niklas; White, Nicholas J.; Hayden, Frederick G.; Wong, Edward H. C.; Ka Shing Wong; Cockram, Clive S.; Sung, Joseph J. Y.; Hui, David S. C.
- Abstract
We report acute encephalopathy associated with influenza A infection in 3 adults. We detected high cerebrospinal fluid (CSF) and plasma concentrations of CXCL8/IL-8 and CCL2/MCP-1 (CSF/plasma ratios >3), and interleukin-6, CXCL10/IP-10, but no evidence of viral neuroinvasion. Patients recovered without sequelae. Hyperactivated cytokine response may play a role in pathogenesis.
- Subjects
INFLUENZA A virus; CEREBROSPINAL fluid; INTERLEUKIN-6; CYTOKINES; DISEASES in older people; NEUROLOGY
- Publication
Emerging Infectious Diseases, 2010, Vol 16, Issue 1, p139
- ISSN
1080-6040
- Publication type
Article
- DOI
10.3201/eid1601.090077