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- Title
Epileptic seizures associated with progressive multifocal leukoencephalopathy in HIV-infected patients in Korea.
- Authors
Kim, Hyun Kyung; Kang, Ji Yun; Lee, Seo-Young
- Abstract
We investigated the incidence and risk factors of seizures related to progressive multifocal leukoencephalopathy (PML) in Korean patients infected with HIV. Of the 34 patients, 14 (41.2%) developed epileptic seizures during a median follow-up of 82 months. The median time from PML diagnosis to seizure onset was 44 months, ranging from 0 to 133 months. Patients with PML who developed seizures more commonly had cognitive impairment and multiple or diffuse lesions on brain MRI. These findings highlight the increased seizure risk among HIV-infected patients with PML at any stage of the disease, particularly in cases with extensive involvement.
- Subjects
SOUTH Korea; PROGRESSIVE multifocal leukoencephalopathy; JOHN Cunningham virus; EPILEPSY; HIV-positive persons; KOREANS; BRAIN damage; DEEP brain stimulation
- Publication
Journal of NeuroVirology, 2023, Vol 29, Issue 3, p325
- ISSN
1355-0284
- Publication type
Article
- DOI
10.1007/s13365-023-01136-0