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- Title
NOVEL SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF N-(5BROMO-2-(5-PHENYL-1,3,4-OXADIAZOL-2-YL)NAPHTHA[2,1-B]FURAN-1-YL)ACETAMIDE AND N-(5-NITRO-2-(5-PHENYL-1,3,4-OXADIAZOL-2-YL)NAPHTHA[2,1-BFURAN-1-YL]ACETAMIDE AND THEIR DERIVATIVES.
- Authors
Nagarsha, K. M.; Sharanakumar, T. M.; Ramesh, D.; Kumar, N. Y. Praveen; Kumarswamy, M. N.; Ramesh, D. R.; Latha, K. P.
- Abstract
The novel derivatives of naphtho-furan such N-(5bromo-2-(5-phenyl-1,3,4-oxadiazol-2-yl)naphtha[2,1-b]furan-1-yl)acetamide (8), N-(5-bromo-2-(hydrazinecarbonyl)naphtha[2,1-b]furan-1-yl]acetamide (7), ethyl-1-acetamido-5-bromonaphtho[2,1-b]furan-2-carboxylate (6), N-(5-nitro-2-(5-phenyl-1,3,4-oxadiazol-2-yl)naphtha[2,1-bfuran-1-yl]acetamide (5),N-(2-(hydrazinecarbonyl)-5-nitronaphtho[2,1-b]furan-1-yl)acetamide (4), ethyl-1-acetamido-5-nitrpnaphtho[2,1-b]furan-2-carboxylate (3), are prepared by ethyl-1-acetamidonaphtho[2,1-b]furan-2-carboxyate and ethyl 1-aminonaphtho[2,1-b]furan-2-carboxylate. All newly synthesized compounds were confirmed by Mass, NMR, and FTIR spectroscopic techniques. Those compounds were used for antimicrobial activity it exhibits good antibacterial and anti-functional activity.
- Subjects
ACETAMIDE derivatives; ANTI-infective agents; ACETAMIDE; NAPHTHA; CHEMICAL synthesis; ANTIBACTERIAL agents
- Publication
Rasayan Journal of Chemistry, 2023, Vol 16, Issue 1, p167
- ISSN
0974-1496
- Publication type
Case Study
- DOI
10.31788/RJC.2023.1618088