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- Title
Incidence and Prevalence of Unrecognized Myocardial Infarction in People With Diabetes.
- Authors
MACDONALD, MICHAEL R.; PETRIE, MARK C.; HOME, PHILIP D.; KOMAJDA, MICHEL; JONES, NIGEL P.; BECK-NIELSEN, HENNING; GOMIS, RAMON; HANEFELD, MARKOLF; POCOCK, STUART J.; CURTIS, PAULA S.; McMURRAY, JOHN J.V.
- Abstract
OBJECTIVE--To examine the prevalence and incidence of unrecognized myocardial infarction in a contemporary population with type 2 diabetes. RESEARCH DESIGN AND METHODS--We performed a retrospective analysis of the electrocardiograms (ECGs) recorded at baseline and after 2 years for the first 1,004 type 2 diabetic individuals to be randomized in the Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycemia in Diabetes (RECORD) study. RESULTS--ECGs suitable for analysis were obtained from 669 participants. The prevalence of unrecognized Q-wave myocardial infarction at baseline was 1.9% (n = 13). The incidence of unrecognized Q-wave myocardial infarction at the end of 2 years of follow-up was 1.5/1,000-person-years (n = 2). One-third (13 of 39) of prevalent and one-quarter (2 of 8) of incident myocardial infarctions were unrecognized. CONCLUSIONS--Although the prevalence and incidence of myocardial infarction was low, unrecognized Q-wave myocardial infarctions made up a substantial proportion of all events.
- Subjects
MYOCARDIAL infarction; TYPE 2 diabetes; ELECTROCARDIOGRAPHY; ROSIGLITAZONE; TREATMENT of diabetes; THERAPEUTICS
- Publication
Diabetes Care, 2011, Vol 34, Issue 6, p1394
- ISSN
0149-5992
- Publication type
Article
- DOI
10.2337/dc10-2398